%0 Journal Article %T 半乳糖凝集素-3与心房颤动的研究进展 %T Research advance in Galectin-3 and atrial fibrillation %A 李庆宽(综述),覃绍明(审校) %A LI,Qing kuan %A QIN,Shao ming %J 中国临床新医学 %J CHINESE JOURNAL OF NEW CLINICAL MEDICINE %@ 1674-3806 %V 12 %N 1 %D 2019 %P 107-110 %K 心房颤动;半乳糖凝集素-3;心房纤维化;炎症反应 %K Atrial fibrillation;Galectin-3;Atrail fibrosis;Inflammatory response %X [摘要] 心房颤动(简称房颤)是一种具有慢性炎性病理过程的疾病,其发生发展过程中始终伴随着炎症反应。半乳糖凝集素-3作为一种炎症因子,参与细胞黏附、增殖及凋亡等过程。近年来研究发现,半乳糖凝集素-3在房颤的形成和发展中发挥着重要的作用,参与了房颤的形成、进展过程,是房颤重要的生化标志物,并有望成为房颤治疗的新靶点。该文对半乳糖凝集素-3与房颤关系的研究进展作一综述。 %X [Abstract] It has been confirmed that atrial fibrillation is a chronic inflammatory pathological process, and its occurrence and development are always accompanied by inflammatory response. Galectin-3 is an inflammatory factor, involving in the process of cell adhesion,proliferation and apoptosis. Recent studies have found that galectin-3 plays an important role in the occurrence and development of atrial fibrillation, and is an important biochemical marker for atrial fibrillation. Galecin-3 is expected to become a new target for atrial fibrillation treatment. We review the research progress of the galectin-3 and atrial fibrillation in this paper. %R 10.3969/j.issn.1674-3806.2019.01.31 %U http://www.zglcxyxzz.com/ch/reader/view_abstract.aspx %1 JIS Version 3.0.0