| 摘要: |
| ［摘要］ 目的 比较选择性激光小梁成形术（SLT）和曲伏前列腺素滴眼液治疗残余性晚期原发性开角型青光眼（POAG）的效果。方法 采用非随机对照研究，将30例30眼患者分为SLT组15例（接受SLT治疗）和药物组15例（接受0.004%曲伏前列腺素滴眼液治疗），观察两组治疗前、治疗后1 d、1周、1个月、3个月及6个月眼压变化情况。结果 两组治疗前眼压比较差异无统计学意义（P>0.05），两组治疗后各个时间点的眼压均较术前下降，差异有统计学意义（P<0.05）。治疗后3个月，两组眼压比差异无统计学意义（P>0.05），其余时间点，两组眼压比较差异均有统计学意义（P<0.05）。与治疗前的基线眼压相比，治疗后1 d，SLT组眼压下降的幅度大于药物组，其余各时间点药物组眼压下降的幅度均大于SLT组。SLT组患者治疗后眼压的波动大于药物组。两组并发症发生率比较差异无统计学意义（P>0.05）。结论 SLT可有效降低残余性晚期POAG患者的眼压，但降压效果及稳定性逊于曲伏前列腺素滴眼液。 |
| 关键词: 选择性激光小梁成形术 晚期原发性开角型青光眼 残余性青光眼 眼压 曲伏前列腺素滴眼液 |
| DOI：10.3969/j.issn.1674-3806.2018.09.05 |
| 分类号:R 775.2 |
| 基金项目:广西卫计委科研课题(编号：Z2015349) |
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| Comparison of the efficacy in treatment of residual advanced primary open-angle glaucoma between two different methods |
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ZHANG Shao-yang, LI Li, ZHONG Shan
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Department of Ophthalmology, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To compare the effects of selective laser trabeculoplasty(SLT) and travoprost eye drops on the treatment of residual advanced primary open-angle glaucoma(POAG). Methods A total of 30 patients(30 eyes) were divided into two groups using a non-randomized controlled trial methed. The patients in the SLT-treated group received SLT treatment, and the patients in the drug-treated group received 0.004% travoprost eye drops treatment. The patients were followed up for 1 day, 1 week, 1 month, 3 months and 6 months after treatment. The changes of intraocular pressure(IOP) were observed before and after treatment. Results Before treatment, the difference of IOP between the SLT-treated group and the drug-treated group was not statistically significant(P>0.05). From 1 day to 6 months after treatment, the IOPs were significantly lower than those before treatment in the two groups(P<0.05). 3 months after treatment, there was no significant difference in IOP between the SLT-treated group and the drug-treated group(P>0.05), while at the other time points, there were significant differences in IOPs between the two groups(P<0.05). Compared with the baseline IOP before treatment, the IOPs of the two groups were significantly different 1 day, 1 week, 1 month, and 6 months after treatment(P<0.05). The decrease of IOP in the SLT-treated group was larger than that in the drug-treated group on the 1st day after treatment, and the decrease of IOP in the drug-treated group was greater than that in the SLT-treated group at the other time points. The fluctuation of IOP in the SLT-treated group was greater than that in the drug-treated group after treatment. There was no significant difference in the incidence of postoperative complications between the two groups（P>0.05）. Conclusion SLT can effectively reduce the intraocular pressure of residual advanced POAG, but the effect and stability of IOP reduction are inferior to those of travoprost eye drops. |
| Key words: Selective laser trabeculoplasty Advanced primary open-angle glaucoma Residual glaucoma Intraocular pressure(IOP) Travoprost eye drops |
