引用本文:郭 杰.宫腔镜子宫内膜射频消融术治疗围绝经期功血的临床疗效及安全性观察[J].中国临床新医学,2018,11(10):1027-1030.
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宫腔镜子宫内膜射频消融术治疗围绝经期功血的临床疗效及安全性观察
郭 杰
475500 河南,开封新区新圣玛医院妇产科
摘要:
[摘要] 目的 探讨宫腔镜子宫内膜射频消融术治疗围绝经期功能失调性子宫出血(功血)的临床疗效以及安全性。方法 选取该院妇产科2013-07~2016-06收治的围绝经期功血患者116例,采用随机数字表法分为研究组和对照组,每组58例。对照组行子宫内膜电切术治疗,研究组行宫腔镜子宫内膜射频消融术治疗,比较两组的手术时间、术中出血量、住院时间、临床疗效以及术后并发症的发生率,对所有患者随访6个月,比较两组治疗前后的血红蛋白(Hb)水平变化。结果 与对照组比较,研究组手术时间、术中出血量以及住院时间均减少,差异有统计学意义(P<0.05);研究组临床总有效率高于对照组,但差异统计学意义(P>0.05);研究组术后并发症发生率为3.45%,低于对照组的17.24%,差异有统计学意义(P<0.05);两组患者治疗后Hb水平均高于治疗前,差异有统计学意义(P<0.05);两组治疗后Hb水平比较,差异统计学意义(P>0.05)。结论 宫腔镜子宫内膜射频消融术治疗围绝经期功血的临床效果比较确切,对患者的损伤较小,术后并发症较少,能有效缓解患者的贫血情况,值得在临床上推广应用。
关键词:  宫腔镜  子宫内膜射频消融术  子宫内膜电切术  围绝经期  功能失调性子宫出血
DOI:10.3969/j.issn.1674-3806.2018.10.20
分类号:R 711.52
基金项目:
Clinical effects and safety of endometrial radiofrequency ablation by hysteroscopy in treatment of perimenopausal dysfunctional uterine bleeding
GUO Jie
Department of Gynecology and Obstetrics, New Shengma Hospital of Kaifeng New District, Henan 475500, China
Abstract:
[Abstract] Objective To observe the clinical effects and safety of endometrial radiofrequency ablation by hysteroscopy in treatment of perimenopausal dysfunctional uterine bleeding. Methods From July 2013 to June 2016, a total of 116 patients with perimenopausal dysfunctional uterine bleeding in our hospital were enrolled, and were randomly divided into the research group treated with hysteroscopic endometrial electroresection and the control group treated with hysteroscopic endometrial radiofrequency ablation, with 58 cases in each group. The operation time, intraoperative blood volume, hospital stay, clinical effects and incidence of postoperative complications were compared between the two groups. All the patients were followed-up for 6 months, and the changes of the levels of hemoglobin(Hb) were compared before and after treatment. Results Compared with those in the control group, the operation time, intraoperative blood volume and hospital stay of the research group were significantly reduced(P<0.05). The total effective rate of the research group was slightly higher than that of the control group, without a significant difference between the two groups(P>0.05). The incidence of postoperative complications of the research group(3.45%) was significantly lower that that of the control group(17.24%)(P<0.05). The levels of Hb in the two groups after the treatment were significantly higher than those before the treatment(P<0.05). There were no significant differences in the levels of Hb between the two groups after treatment(P>0.05). Conclusion Hysteroscopic endometrial radiofrequency ablation is effective in treatment of perimenopausal dysfunctional uterine bleeding,which causes less injury and less complications, and effectively alleviates anemia in the patients after the operation.
Key words:  Hysteroscopy  Endometrial radiofrequency ablation  Endometrial electroresection  Perimenopausal  Dysfunctional uterine bleeding