引用本文:贾永梅.常规三联疗法联合丹参注射液治疗胃溃疡的临床效果及安全性观察[J].中国临床新医学,2018,11(11):1145-1147.
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常规三联疗法联合丹参注射液治疗胃溃疡的临床效果及安全性观察
贾永梅
276000 山东,临沂市康复医院内科
摘要:
[摘要] 目的 观察常规三联疗法联合丹参注射液应用于胃溃疡治疗的临床疗效和安全性。方法 随机将住院治疗的140例胃溃疡患者分为观察组70例和对照组70例。对照组采取常规三联疗法治疗,观察组采用常规三联疗法联合丹参注射液治疗,均连续治疗一个月。观察并比较两组患者的临床症状改善情况、溃疡的愈合程度以及幽门螺杆菌(HP)清除情况及不良反应发生情况。结果 观察组显效44例,有效22例,效4例;对照组显效33例,有效20例,效17例。观察组临床疗效优于对照组(P<0.05)。观察组的药物不良反应发生率为2.86%,低于对照组的11.43%(P<0.05)。结论 使用常规三联疗法联合丹参注射液治疗胃溃疡可以取得很好的临床疗效,安全性也可以得到保障。
关键词:  常规三联疗法  丹参注射液  胃溃疡
DOI:10.3969/j.issn.1674-3806.2018.11.22
分类号:R 573
基金项目:
Clinical effect and safety of routine triple therapy combined with Danshen injection in treatment of gastric ulcer
JIA Yong-mei
Department of Internal Medicine, Linyi Rehabilitation Hospital, Shandong 276000, China
Abstract:
[Abstract] Objective To observe the clinical effect and safety of routine triple therapy combined with Danshen injection in treatment of gastric ulcer. Methods 140 patients with gastric ulcer were selected in our hospital. All of the patients were randomly divided into the observation group and the control group, with 70 cases in each group. The control group received the routine triple therapy, and the observation group was treated with Danshen injection plus the same treatment as the control group. All the patients were treated continuously for one month. The clinical symptoms, healing degree of ulcer, HP clearance and adverse reactions were compared between the two groups. Results In the observation group, 44 cases were markedly effective, 22 cases effective, and 4 cases ineffective. In the control group, 33 cases were markedly effective, 20 cases effective, and 17 cases ineffective. The clinical effect of the observation group was better than that of the control gruop(P<0.05). The incidence of adverse reactions in the observation group(2.86%) was lower than that in the control group(11.43%)(P<0.05). Conclusion  The routine triple therapy combined with Danshen injection is safe and effective in treatment of gastric ulcer.
Key words:  Routine triple therapy  Danshen injection  Gastric ulcer