引用本文:李庆宽(综述),覃绍明(审校).半乳糖凝集素-3与心房颤动的研究进展[J].中国临床新医学,2019,12(1):107-110.
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半乳糖凝集素-3与心房颤动的研究进展
李庆宽(综述),覃绍明(审校)
530021 南宁,广西壮族自治区人民医院心内科
摘要:
[摘要] 心房颤动(简称房颤)是一种具有慢性炎性病理过程的疾病,其发生发展过程中始终伴随着炎症反应。半乳糖凝集素-3作为一种炎症因子,参与细胞黏附、增殖及凋亡等过程。近年来研究发现,半乳糖凝集素-3在房颤的形成和发展中发挥着重要的作用,参与了房颤的形成、进展过程,是房颤重要的生化标志物,并有望成为房颤治疗的新靶点。该文对半乳糖凝集素-3与房颤关系的研究进展作一综述。
关键词:  心房颤动  半乳糖凝集素-3  心房纤维化  炎症反应
DOI:10.3969/j.issn.1674-3806.2019.01.31
分类号:R 541.6
基金项目:
Research advance in Galectin-3 and atrial fibrillation
LI Qing-kuan, QIN Shao-ming
Department of Cardiology, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
Abstract:
[Abstract] It has been confirmed that atrial fibrillation is a chronic inflammatory pathological process, and its occurrence and development are always accompanied by inflammatory response. Galectin-3 is an inflammatory factor, involving in the process of cell adhesion,proliferation and apoptosis. Recent studies have found that galectin-3 plays an important role in the occurrence and development of atrial fibrillation, and is an important biochemical marker for atrial fibrillation. Galecin-3 is expected to become a new target for atrial fibrillation treatment. We review the research progress of the galectin-3 and atrial fibrillation in this paper.
Key words:  Atrial fibrillation  Galectin-3  Atrail fibrosis  Inflammatory response