引用本文:张 琦,韩 斌.术前平均血小板体积与早期直肠癌复发的相关性探讨[J].中国临床新医学,2019,12(3):298-301.
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术前平均血小板体积与早期直肠癌复发的相关性探讨
张 琦,韩 斌
450014 河南,郑州大学第二临床学院普外科
摘要:
[摘要] 目的 探讨术前平均血小板体积(mean platelet volume,MPV)与早期直肠癌复发的关系。方法 选择行外科手术治疗的早期直肠癌患者50例,分为无复发组(41例)和复发组(9例),收集两组患者围手术期临床资料,并进行统计分析。结果 术前MPV水平复发组为(12.46±1.95)fL,高于无复发组的(9.85±1.34)fL,差异有统计学意义(P<0.05)。Logistic回归分析显示术前MPV(OR=3.726,95%CI=1.216~11.413),CA19-9(OR=0.010,95%CI=0.000~0.449)是早期直肠癌术后复发的独立影响因素。结论 术前MPV水平与早期直肠癌有相关性,MPV可能成为预测早期直肠癌患者术后复发的检测指标。
关键词:  平均血小板体积  血小板  早期直肠癌  血常规  炎症
DOI:10.3969/j.issn.1674-3806.2019.03.15
分类号:R 735.3
基金项目:
Discussion of association of preoperative mean platelet volume with early rectal carcinoma recurrence
ZHANG Qi, HAN Bin
Department of General Surgery, the Second Clinical College of Zhengzhou University, Henan 450014, China
Abstract:
[Abstract] Objective To investigate the relationship of preoperative mean platelet volume(MPV) with early rectal carcinoma recurrence. Methods The study consisted of 50 patients with a diagnosis of early rectal carcinoma and the patients were divided into recurrence-free group(n=41) and recurrence group(n=9). The perioperative clinical data of the patients were collected and were statistically analyzed. Results The level of preoperative MPV in the recurrence group[(12.46±1.95)fL] was higher than that in the recurrence-free group[(9.85±1.34)fL], P<0.05. Logistic regression models revealed that MPV significantly associated with recurrence and metastasis and preoperative MPV(OR=3.726, 95%CI=1.216~11.413) and CA19-9(OR=0.010, 95%CI=0.000~0.449) were independent risk factors for postoperative recurrence of early rectal carcinoma. Conclusion The level of preoperative MPV is associated with early rectal carcinoma, and MPV may be used for predicting the recurrence of early rectal carcinoma after operation.
Key words:  Mean platelet volume(MPV)  Platelet  Early rectal carcinoma  Blood routine examination  Inflammation