| 摘要: |
| ［摘要］ 脂肪是三大供能物质之一，脂肪组织则是人体重要的能量仓库，脂肪因子的发现也揭示了脂肪组织的另一个重要身份——内分泌器官。脂肪组织分泌的细胞因子称为脂肪因子，脂肪因子趋化素（chemerin）是近年新发现的脂肪因子，研究发现chemerin水平与高血压、冠状动脉粥样硬化性心脏病及心力衰竭等疾病密切相关。该文就近年来研究发现的chemerin在心血管疾病中的作用机制进行综述。 |
| 关键词: 脂肪因子 趋化素 心血管疾病 作用机制 |
| DOI：10.3969/j.issn.1674-3806.2019.03.25 |
| 分类号:R 364 |
| 基金项目: |
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| Advances in the relationship between chemerin and cardiovascular diseases |
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HU Zhen, ZOU De-ling
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Department of Cardiology, Shengjing Hospital of China Medical University, Shenyang 110004, China
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| Abstract: |
| ［Abstract］ Fat is one of the three main energy sources. Adipose tissue is the important energy storage. The discovery of adipokine reveals another important identity of adipose tissue—endocrine organ. Adipokines are cytokines secreted by adipose tissue. Chemerin is a newly discovered adipokine which is closely related to high blood pressure, coronary atherosclerosis and heart failure. In this paper, the mechanisms of chemerin in cardiovascular diseases are reviewed. |
| Key words: Adipokine Chemerin Cardiovascular diseases Mechanism of action |
