引用本文:宋朝阳,朱良付,郑春玲,王丽娜,邢 莹.急性缺血性脑卒中颅内血栓病理研究进展[J].中国临床新医学,2019,12(6):604-607.
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急性缺血性脑卒中颅内血栓病理研究进展
宋朝阳,朱良付,郑春玲,王丽娜,邢 莹
450003 郑州,河南省人民医院 河南省脑血管病医院(郑州大学人民医院)脑血管病介入科(宋朝阳,朱良付,王丽娜,邢 莹);462000 河南,漯河市中心医院神经内科(宋朝阳,郑春玲)
摘要:
[摘要] 急性缺血性脑卒中(AIS)占新发脑卒中总体的69.6%~70.8%。血管内治疗可去除闭塞颅内大血管的血栓和改善患者预后。分析颅内血栓的组成成分、来源、物理特性及其与血管之间的相互作用有助于判定AIS开通策略、临床预后、病因及二级预防。该文综述了近年来发表的有关AIS颅内血栓的研究文献,指出了未来该领域内的部分研究方向。
关键词:  卒中  缺血  血管内  血栓切除术  血栓  病理
DOI:10.3969/j.issn.1674-3806.2019.06.06
分类号:R 743
基金项目:河南省医学科技攻关计划重点项目(编号:201502019);河南省自然科学基金项目(编号:182300410315);河南省医学科技攻关计划项目(编号:201702343)
Advances in pathological research on intracranial thrombosis in acute ischemic stroke
SONG Zhao-yang, ZHU Liang-fu, ZHENG Chun-ling, et al.
Department of Interventional Therapy of Cerebrovascular Diseases, Henan Provincial People′s Hospital, Henan Cerebrovascular Hospital(People′s Hospital of Zhengzhou University), Zhengzhou 450003, China
Abstract:
[Abstract] Acute ischemic stroke(AIS) accounts for 69.6%~70.8% of all new stroke cases. Endovascular thrombectomy(ET) can remove the thrombi from occluded intracranial large vessels and improve the outcome of AIS. The components, sources, physical characteristics of intracranial thrombi and their interactions with blood vessels might be helpful for the judgement of recanalization strategies, clinical prognosis, etiology and secondary prevention. This review summarizes the literatures published in recent years and predicts some further researches of this field in the future.
Key words:  Stroke  Ischemia  Endovascular  Thrombectomy  Thrombus  Pathology