| 摘要: |
| ［摘要］ 目的 探讨不同输入动脉对中央型肺癌灌注参数的影响。方法 对48例原发型中央型肺癌患者行CT灌注成像扫描，分别选择胸主动脉及主肺动脉干为输入动脉进行灌注分析，比较相同病灶的灌注参数以及不同病理类型的灌注参数。结果 48例中央型肺癌患者以胸主动脉为输入动脉肺癌的血流量（BF）高于以主肺动脉干为输入动脉,差异有统计学意义（P<0.05）；以胸主动脉为输入动脉肺癌的PS、TTP、MTT低于以主肺动脉干为输入动脉，差异有统计学意义（P<0.05）；以胸主动脉为输入动脉肺癌的BV略低于以主肺动脉干为输入动脉，但差异无统计学意义（P>0.05）。48例中央型肺癌中小细胞癌13例，鳞癌16例，腺癌19例，以胸主动脉为输入动脉时不同病理类型的灌注参数差异无统计学意义（P>0.05），以主肺动脉干为输入动脉时不同病理类型的灌注参数差异无统计学意义（P>0.05）。结论 研究发现不同输入动脉对中央型肺癌的灌注参数有影响,用单入口灌注软件对中央型肺癌进行研究时应选择其主要供血动脉胸主动脉为输入动脉；灌注参数不适用于中央型肺癌病理类型的评估。 |
| 关键词: 肺肿瘤 灌注成像 体层摄影术 X线计算机 |
| DOI：10.3969/j.issn.1674-3806.2019.12.17 |
| 分类号:R 734；R 445 |
| 基金项目: |
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| Study on the influence of input arterial selection on perfusion parameters of central lung cancer |
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YANG Ting, WANG Xin-wen, MA Ai-xin, et al.
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Department of Medical Imaging, Shanxi Medical University, Taiyuan 030000, China
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| Abstract: |
| ［Abstract］ Objective To investigate the effects of different input arteries on perfusion parameters of central lung cancer. Methods Computed tomography(CT) perfusion imaging was performed in 48 patients with primary central lung cancer. The thoracic aorta and the main pulmonary trunk were selected as the input arteries for perfusion analysis, and the perfusion parameters of the same lesions and different pathological types were compared. Results The BF value of lung cancer with the thoracic aorta as the input artery was higher than that with the main pulmonary artery as the input artery(P<0.05). The PS, TTP and MTT values of lung cancer with the thoracic aorta as the input artery were lower than those with the main pulmonary artery as the input artery(P<0.05). The BV of lung cancer with the thoracic aorta as the input artery was slightly lower than that with the main pulmonary artery as the input artery, but the difference was not statistically significant(P>0.05). Among the 48 cases of central lung cancer, 13 cases were small cell carcinoma, and 16 cases were squamous cell carcinoma and 19 cases were adenocarcinoma. There were no significant differences in the perfusion parameters of different pathological types when the thoracic aorta was used as the input artery(P>0.05), and there were no significant differences in the perfusion parameters of different pathological types when the main pulmonary artery was used as the input artery(P>0.05). Conclusion It is found that the perfusion parameters of central lung cancer are affected by different input arteries. In the study of central lung cancer with single port perfusion software, thoracic aorta should be chosen as the input artery. Perfusion parameters are not applicable to the assessment of the pathological types of central lung cancer. |
| Key words: Lung tumors Perfusion imaging Tomography X-ray computer |
