引用本文:秦志强,马 刚,钟晓刚.新型冠状病毒肺炎诊断和抗病毒治疗现状[J].中国临床新医学,2020,13(5):429-435.
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新型冠状病毒肺炎诊断和抗病毒治疗现状
秦志强,马 刚,钟晓刚
530021 南宁,广西壮族自治区人民医院呼吸与危重症医学科、感染性疾病科(秦志强),广西壮族自治区人民医院新冠肺炎防控指挥部(马 刚,钟晓刚)
摘要:
[摘要] 2019年12月以来,新型冠状病毒肺炎疫情快速影响全球。新型冠状病毒肺炎患者是最主要传染源,人际间传播性强,飞沫传播是最主要传播途径。潜伏期多数在7 d内。常见临床表现有发热、呼吸道症状、乏力,外周血淋巴细胞计数正常或减少,胸部影像学检查以两肺外周多发磨玻璃影常见。诊断依赖于流行病学史和临床表现,确诊病例需要呼吸道或血液样本新型冠状病毒核酸检测阳性。尽管有研究报道多种药物抗病毒有效,但仍缺少随机对照研究证实其有效性。中西医结合治疗可能是有效的中国特色治疗方法。
关键词:  新型冠状病毒肺炎  发热  呼吸道症状  淋巴细胞  诊断
DOI:10.3969/j.issn.1674-3806.2020.05.01
分类号:R 563.1
基金项目:广西科技厅重点研发计划项目(编号:桂AB16380218);广西医疗卫生适宜技术研究与开发课题(编号:S201315-05)
Current situation of diagnosis and antiviral therapy for coronavirus disease 2019
QIN Zhi-qiang, MA Gang, ZHONG Xiao-gang
Department of Pulmonary and Critical Care Medicine, Department of Infectious Diseases, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
Abstract:
[Abstract] Since December 2019, coronavirus disease 2019(COVID-19) has rapidly affected the whole world. The patients with COVID-19 is the most important source of the novel coronavirus(named severe acute respiratory syndrome coronavirus 2,SARS-CoV-2), which predominantly transmits from person to person via droplets. The interpersonal transmission is strong. Most of the patients′ incubation period is within 7 days. The common clinical manifestations include fever, respiratory symptoms, fatigue, normal or reduced peripheral blood lymphocyte count, and multiple bilateral patchy ground-glass opacity in the periphery of the two lungs in computed tomography(CT) findings. Diagnosis depends on epidemiological history and clinical manifestations, and a confirmed case requires a respiratory or blood sample that tests positive for novel coronavirus nucleic acid. Although the effects of several drugs on novel coronavirus have been reported, there is still a lack of randomized controlled clinical trials to confirm their effectiveness. Combination of Traditional Chinese Medicine and Western Medicine may be an effective treatment with Chinese characteristics.
Key words:  Coronavirus disease 2019(COVID-19)  Fever  Respiratory symptoms  Lymphocytes  Diagnosis