引用本文:赖彦华,徐钰驹,杨建荣.劈离式肝移植技术及研究进展[J].中国临床新医学,2020,13(12):1208-1212.
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劈离式肝移植技术及研究进展
赖彦华,徐钰驹,杨建荣
530021 南宁,广西壮族自治区人民医院移植科,广西门静脉高压防治研究重点实验室
摘要:
[摘要]  肝移植是目前晚期肝病患者唯一有效的治疗手段,但是该术式仍受限于紧张的供肝数量,使得大量等待移植的晚期肝病患者错失了手术机会,在此背景下劈离式肝移植应运而生,提高了供肝利用率,在一定程度上缓解了供肝的紧张。起步阶段劈离式肝移植受者的预后并不理想,并发症发生率高,随着技术的进步,劈离式肝移植受者的生存率逐渐接近全肝移植受者,且并发症发生率较前显著降低,越来越多的移植中心已将劈离式肝移植术作为优先选择的术式。该文对劈离式肝移植技术及其研究进展作一综述。
关键词:  脑死亡供体  劈离式肝移植  预后  术后并发症
DOI:10.3969/j.issn.1674-3806.2020.12.06
分类号:R 657.3
基金项目:广西医疗卫生适宜技术开发与推广应用项目(编号:S2018086)
The technique and research progress of split liver transplantation
LAI Yan-hua, XU Yu-ju, YANG Jian-rong
Department of Organ Transplantation, the People′s Hospital of Guangxi Zhuang Autonomous Region, Guangxi Key Laboratory of Prevention and Treatment of Portal Hypertension, Nanning 530021, China
Abstract:
[Abstract] Liver transplantation is the only effective treatment for patients with advanced liver disease. However, the operation is still limited by the number of liver donors, which makes a large number of patients with advanced liver disease waiting for transplantation miss the opportunity of operation. In this context, split liver transplantation emerges as the times require, which improves the utilization rate of the donor liver and eases the tension of the donor liver to a certain extent. The prognoses of split liver transplantation recipients at the initial stage are not ideal, and they often have a high incidence of complications. With the advancement of technology, the survival rate of split liver transplantation recipients is gradually approaching that of total liver transplantation recipients and the incidence of complications is significantly lower than before. More and more transplantation centers have taken split liver transplantation as the preferred surgical procedure. In this paper, the technique and its research progress of split liver transplantation are summarized.
Key words:  Brain-dead donor  Split liver transplantation  Prognosis  Postoperative complications