| 摘要: |
| ［摘要］ 目的 分析超声联合钼靶检查对肿瘤直径≤2 cm早期浸润性乳腺癌患者豁免前哨淋巴结活检（SLNB）的价值。方法 选取重庆医科大学附属第一医院2018-01～2019-06肿瘤直径≤2 cm且术中行SLNB的122例早期浸润性乳腺癌患者，对其临床资料进行回顾性分析，收集超声、钼靶、MRI及SLNB的结果，分别与术后腋窝淋巴结活检结果（金标准）进行比较。结果 122例患者中，29例患者术后腋窝淋巴结活检结果为阳性。SLNB、超声、MRI及钼靶与金标准的Kappa一致性检验中，Kappa值分别为0.721、0.668、0.620、0.422，差异有统计学意义（P<0.05）；超声、钼靶、MRI两两并联或三者并联诊断与金标准的Kappa检验中，超声并联钼靶的Kappa值最高（Kappa=0.702，P<0.05）。结论 超声联合钼靶诊断腋窝淋巴结转移结果与金标准结果一致性较高，对肿瘤直径≤2 cm早期浸润性乳腺癌患者豁免SLNB提供了有力的证据支撑。 |
| 关键词: 早期浸润性乳腺癌 前哨淋巴结活检 超声 钼靶 腋窝淋巴结转移 |
| DOI：10.3969/j.issn.1674-3806.2021.04.10 |
| 分类号:R 737.9 |
| 基金项目: |
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| Analysis of the value of ultrasound combined with molybdenum target to avoid sentinel lymph node biopsy for early invasive breast cancer |
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CHEN Huan, YANG Guang-lun, YANG Luo, et al.
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Department of Endocrinology and Breast Surgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
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| Abstract: |
| ［Abstract］ Objective To analyze the value of ultrasound combined with molybdenum target in early invasive breast cancer patients with tumor diameter≤2 cm to avoid sentinel lymph node biopsy(SLNB). Methods A retrospective study was conducted on 122 early invasive breast cancer patients with tumor diameter≤2 cm and SLNB was performed on them during the operation in the First Affiliated Hospital of Chongqing Medical University from January 2018 to June 2019. The results of ultrasound, molybdenum target, MRI and SLNB were collected and compared with the results of postoperative axillary lymph node biopsy(gold standard) respectively. Results Of the 122 patients, 29 patients showed positive results of postoperative axillary lymph node biopsy. In the Kappa consistency test of SLNB, ultrasound, MRI and molybdenum target with gold standard, the Kappa values were 0.721, 0.668, 0.620, 0.422, respectively, and the difference was statistically significant(P<0.05). In the Kappa test of ultrasound, molybdenum target and MRI in the combination of pairwise or triple diagnosis with gold standard, the Kappa value of ultrasound combined with molybdenum target was the highest(Kappa=0.702, P<0.05). Conclusion The result of ultrasound combined with molybdenum target in the diagnosis of axillary lymph node metastasis is relatively highly consistent with that of the gold standard, which provides strong evidence support for the early invasive breast cancer patients with tumor diameter≤2 cm to avoid SLNB. |
| Key words: Early invasive breast cancer Sentinel lymph node biopsy(SLNB) Ultrasound Molybdenum target Axillary lymph node metastasis |
