引用本文:陈 斌,吴显儒,凌 政,黄天丽,杨伟良,罗 姬.丁苯酞注射液联合智能机器手治疗急性脑梗死偏瘫手患者的疗效及对脑血流速度的影响分析[J].中国临床新医学,2021,14(6):582-586.
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丁苯酞注射液联合智能机器手治疗急性脑梗死偏瘫手患者的疗效及对脑血流速度的影响分析
陈 斌,吴显儒,凌 政,黄天丽,杨伟良,罗 姬
537400 广西,北流市人民医院神经内科三区
摘要:
[摘要] 目的 观察丁苯酞注射液联合智能机器手治疗急性脑梗死偏瘫手患者的疗效及对患者脑血流速度的影响。方法 选择2019年3月至2020年3月北流市人民医院收治的急性脑梗死偏瘫手患者80例,采用随机数字表法分为研究组和对照组,每组40例。对照组患者采用常规方法进行治疗,研究组患者在常规治疗方法基础上加用丁苯酞氯化钠注射液和智能机器手进行治疗。比较两组患者治疗前、治疗后10 d、治疗后20 d的美国国立卫生院卒中量表(NIHSS)评分、日常生活功能(ADL)评分、手最大握力、夹指压力以及脑血流情况。结果 治疗后两组NIHSS评分均呈下降趋势,在治疗后10 d和治疗后20 d,研究组的NIHSS评分均显著低于对照组(P<0.05)。治疗后两组双侧大脑前动脉(ACA)、中动脉(MCA)、后动脉(PCA)的峰值流速(Vp)和平均血流速度(Vm)水平均呈上升趋势,在治疗后10 d和治疗后20 d,研究组的ACA、MCA、PCA的Vp和Vm水平均显著高于对照组(P<0.05)。治疗后两组ADL评分、最大握力和夹指压力均呈上升趋势,在治疗后10 d和治疗后20 d,研究组的ADL评分、最大握力和夹指压力水平均显著高于对照组(P<0.05)。研究组总有效率为92.50%,对照组总有效率为75.00%,两组比较差异有统计学意义(P<0.05)。结论 丁苯酞注射液联合智能机器手治疗急性脑梗死偏瘫手患者的临床疗效显著,能有效改善患者神经缺损及脑缺血区血流灌注,有助于提高患者日常生活能力。
关键词:  丁苯酞注射液  急性脑梗死  偏瘫手  脑血流速度  智能机器手
DOI:10.3969/j.issn.1674-3806.2021.06.12
分类号:R 459.9
基金项目:广西卫健委科研课题(编号:Z20190624)
Effect of butylphthalide injection combined with intelligent robot hand on treatment of hemiplegic hands in acute cerebral infarction patients and its influence on cerebral blood flow velocity
CHEN Bin, WU Xian-ru, LING Zheng, et al.
The Third Department of Neurology, Beiliu City People′s Hospital, Guangxi 537400, China
Abstract:
[Abstract] Objective To observe the effect of butylphthalide injection combined with intelligent robot hand on treatment of hemiplegic hands in acute cerebral infarction patients and its influence on cerebral blood flow velocity. Methods Eighty acute cerebral infarction patients with hemiplegic hands adimtted to Beiliu City People′s Hospital during March 2019 and March 2020 were selected, and were divided into study group and control group by random number table method, with 40 cases in each group. The patients in the control group were treated with conventional methods, and the patients in the study group were treated with butylphthalide sodium chloride injection and the intelligent robot hand on the basis of the treatment with the conventional methods. The National Institutes of Health Stroke Scale(NIHSS) score, Activities of Daily Living(ADL) score, maximum hand grip strength, the pressure between the fingers and cerebral blood flow were compared between the two groups before treatment, 10 days and 20 days after treatment. Results After treatment, the NIHSS scores showed a downward trend in the two groups. The NIHSS scores of the study group were significantly lower than those of the control group 10 days and 20 days after treatment(P<0.05). After treatment, the peak blood flow velocity(Vp) and mean blood flow velocity(Vm) levels of anterior cerebral artery(ACA), middle cerebral artery(MCA) and posterior cerebral artery(PCA) showed an upward trend in the two groups. After treatments of 10 days and 20 days, the Vp and Vm levels of ACA, MCA and PCA in the study group were significantly higher than those in the control group(P<0.05). After treatment, the ADL scores, maximum grip strength and the pressure between the fingers showed an upward trend in the two groups. After treatments of 10 days and 20 days, the ADL scores, maximum grip strength and the pressure between the fingers of the study group were significantly higher than those of the control group(P<0.05). The total effective rate was 92.50% in the study group, and 75.00% in the control group, and the difference was statistically significant between the two groups(P<0.05). Conclusion Butylphthalide injection combined with intelligent robot hand has a significant clinical effect on the acute cerebral infarction patients with hemiplegic hands. The combined therapy can effectively improve the patients′ nerve defects and cerebral blood perfusion, and help to improve the patients′ ADL.
Key words:  Butylphthalide injection  Acute cerebral infarction  Hemiplegic hand  Cerebral blood flow velocity  Intelligent robot hand