摘要: |
[摘要] 淋巴上皮瘤样癌(LELC)是一组少见的与病毒感染密切相关的上皮性恶性肿瘤,可发生于全身任何器官。由于发病率低,LELC大样本临床研究缺乏,其发生的病因、发病机制、临床病理及分子病理特点尚不明确。该文就上述几方面进行文献综述,以期能够更好地了解LELC的发病及分子病理特征。 |
关键词: 淋巴上皮瘤样癌 病因 发病机制 分子病理特征 |
DOI:10.3969/j.issn.1674-3806.2021.09.02 |
分类号:R 73 |
基金项目: |
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Progress in molecular pathology of lymphoepithelioma-like carcinoma |
YIN Wen-juan, SU Dan, TAN Wei-hong
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Department of Pathology, Cancer Hospital of the University of Chinese Academy of Sciences(Zhejiang Cancer Hospital); Institute of Basic Medicine and Cancer(IBMC), Chinese Academy of Sciences, Hangzhou 310022, China
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Abstract: |
[Abstract] Lymphoepithelioma-like carcinoma(LELC) is a group of rare epithelial malignant tumors closely related to viral infection, which may occur in any organ of the body.Due to its low incidence, large scale clinical trials of LELC are lacking. The etiology, pathogenesis, clinicopathological and molecular pathological features of LELC are still unclear. This paper reviews the literature on the above aspects to better understand the pathogenesis and molecular pathological features of LELC. |
Key words: Lymphoepithelioma-like carcinoma(LELC) Etiology Pathogenesis Molecular pathological feature |