| 摘要: |
| ［摘要］ 目的 分析高血压住院患者病因构成及合并代谢异常的情况，为高血压防治提供参考。方法 回顾性分析2013年1月至2018年10月广西医科大学第一附属医院收治住院的高血压患者5 773例的临床资料，分析其病因构成和代谢异常情况。结果 高血压住院患者5 773例中，原发性高血压（EH）患者4 376例（75.80%），继发性高血压（SH）患者1 397例（24.20%）。在SH患者中，以原发性醛固酮增多症患者所占的比例最高（46.03%），其次为肾实质性高血压（43.88%）。EH组男性和有高血压家族史的人数比例显著大于SH组（P<0.05）；SH组年龄小于EH组，入院收缩压、舒张压均高于EH组，差异有统计学意义（P<0.05）。EH组脂代谢异常率和糖代谢异常率显著高于SH组（P<0.05），但高尿酸血症发生率显著低于SH组（P<0.05）。结论 EH仍是高血压的主要原因，但SH也占有重要比例。高血压常合并多种代谢异常，但SH若能早诊断、早治疗，代谢异常就可以得到及时处理，避免后期的并发症发生。这应引起临床医师足够重视，有针对性地进行早期筛查。 |
| 关键词: 原发性高血压 继发性高血压 病因构成 代谢异常 |
| DOI：10.3969/j.issn.1674-3806.2021.09.07 |
| 分类号:R 544.1 |
| 基金项目:国家重点研发计划“精准医学”重点专项2016年度立项项目“代谢性疾病专病队列研究”（编号：2016YFC0901200） |
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| Analysis of the etiological composition and concurrent metabolic abnormalities in 5773 hospitalized patients with hypertension |
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LIU Yu-ping, QIN Miao, YANG Hai-yan, et al.
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Department of Endocrinology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To analyze the etiological composition of hypertensive inpatients and their concurrent metabolic abnormalities so as to provide reference for prevention and treatment of hypertension. Methods The clinical data of 5 773 hypertensive patients admitted to the First Affiliated Hospital of Guangxi Medical University from January 2013 to October 2018 were retrospectively analyzed, and their etiological composition and metabolic abnormalities were analyzed. Results Among the 5 773 hospitalized patients with hypertension, 4 376 patients(75.80%) had essential hypertension(EH) and 1 397 patients(24.20%) had secondary hypertension(SH). Among the SH patients, the patients with primary aldosteronism accounted for the highest proportion(46.03%), followed by those with renal parenchymal hypertension(43.88%). The proportion of the males and the patients with a family history of hypertension in the EH group was significantly greater than that in the SH group(P<0.05); the patients in the SH group were younger than those in the EH group. The systolic blood pressure and the diastolic blood pressure in the SH group were higher than those in the EH group on admission, and the differences were statistically significant(P<0.05). The abnormal rates of lipid metabolism and glucose metabolism in the EH group were significantly higher than those in the SH group(P<0.05), but the incidence of hyperuricemia in the EH group was significantly lower than that in the SH group(P<0.05). Conclusion EH is still the main cause of hypertension, but SH also accounts for an important proportion. Hypertension is often associated with a variety of metabolic abnormalities, but if SH can be diagnosed and treated early, metabolic abnormalities can be treated in time to avoid later complications, to which clinicians should pay enough attention and early screening should be targeted. |
| Key words: Essential hypertension(EH) Secondary hypertension(SH) Etiological composition Metabolic abnormality |
