引用本文:何江涛,薛贞龙,王 苇,赵 义.CT小肠造影在鉴别克罗恩病活动分期中的应用价值[J].中国临床新医学,2022,15(9):832-835.
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CT小肠造影在鉴别克罗恩病活动分期中的应用价值
何江涛,薛贞龙,王 苇,赵 义
225009 江苏,扬州大学附属医院医学影像中心放射科
摘要:
[摘要] 目的 探讨CT小肠造影(CTE)在鉴别克罗恩病(CD)活动分期中的应用价值。方法 选择2019年6月至2021年12月扬州大学附属医院收治的60例CD患者的临床资料。依据克罗恩病活动指数(CDAI)评分将其分为A组(CDAI评分≤220分,缓解期和轻度活动期,31例)和B组(CDAI评分≥221分,中、重度活动期,29例)。采用二元logistic回归分析与CD活动分期关联的参数指标。结果 B组肠壁厚度、动脉期肠壁CT值、静脉期肠壁CT值大于A组,出现肠壁分层强化、梳齿征、系膜脂肪密度增加的比例较A组更高,差异有统计学意义(P<0.05)。二元logistic回归分析结果显示,肠壁厚度[OR(95%CI):3.470(1.178~10.223)]、静脉期肠壁CT值[OR(95%CI):1.289(1.067~1.557)]和肠壁分层强化[OR(95%CI):6.784(1.027~44.759)]与CD活动分期具有显著关联性。结论 CTE的肠壁厚度、肠壁分层强化、静脉期肠壁CT值指标有助于鉴别CD的活动分期。
关键词:  CT小肠造影  克罗恩病  活动分期
DOI:10.3969/j.issn.1674-3806.2022.09.11
分类号:R 445.3
基金项目:扬州市“十三五”科教强卫工程重点学科资助项目(编号:ZDXK201806)
Application value of CT enterography in differentiating active staging of Crohn′s disease
HE Jiang-tao, XUE Zhen-long, WANG Wei, et al.
Department of Radiology, Medical Imaging Center, the Affiliated Hospital of Yangzhou University, Jiangsu 225009, China
Abstract:
[Abstract] Objective To explore the application value of computed tomography(CT) enterography(CTE) in differentiating active staging of Crohn′s disease(CD). Methods The clinical data of 60 CD patients admitted to the Affiliated Hospital of Yangzhou University from June 2019 to December 2021 were selected. According to their different Crohn′s disease activity index(CDAI) scores, the patients were divided into group A(with CDAI scores ≤220 points, during remission and mild activity period, 31 cases) and group B(with CDAI scores ≥221 points, during moderate and severe activity period, 29 cases). Binary logistic regression was used to analyze the parameters associated with the stage of CD activity. Results The intestinal wall thickness, the CT value of the intestinal wall in the arterial phase, and the CT value of the intestinal wall in the venous phase in the group B were greater than those in the group A, and the proportion of the intestinal wall stratified enhancement, the comb-tooth sign, and the increased mesangial fat density in the group B were higher than those in the group A, and the differences were statistically significant(P<0.05). The results of binary logistic regression analysis showed that intestinal wall thickness[OR(95%CI): 3.470(1.178-10.223)], the CT value of the intestinal wall in the venous phase[OR(95%CI): 1.289(1.067-1.557)] and intestinal wall stratification enhancement[OR(95%CI): 6.784(1.027-44.759)] were significantly associated with the active stage of CD. Conclusion Intestinal wall thickness, intestinal wall stratification enhancement, and CT value of the intestinal wall in the venous phase of CTE can help to identify the active stage of CD.
Key words:  Computed tomography(CT) enterography(CTE)  Crohn′s disease(CD)  Active staging