引用本文:薛 阳,徐紫清,张 杰(综述),薛建军(审校).糖尿病肢体缺血再灌注心肌损伤防治的研究进展[J].中国临床新医学,2022,15(10):999-1002.
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糖尿病肢体缺血再灌注心肌损伤防治的研究进展
薛 阳,徐紫清,张 杰(综述),薛建军(审校)
730000 兰州,甘肃中医药大学第一临床医学院(薛 阳,张 杰);730000 兰州,甘肃省中医院麻醉疼痛医学中心(徐紫清,薛建军)
摘要:
[摘要] 糖尿病患者机体内环境长期处于高血糖的状态。当发生肢体缺血再灌注(IR)时,相较于非糖尿病患者的组织和脏器更易受损,且程度更严重。该文就糖尿病肢体IR心肌损伤及其防治作一综述。
关键词:  糖尿病  肢体缺血再灌注  心肌损伤  信号通路  能量代谢紊乱
DOI:10.3969/j.issn.1674-3806.2022.10.22
分类号:R 587
基金项目:甘肃省科技计划资助项目(编号:20JR10RA435);甘肃省中医药管理局科研课题(编号:GZK-2018-29)
Research progress in the prevention and treatment of myocardial injury caused by limb ischemia reperfusion in diabetes mellitus
XUE Yang, XU Zi-qing, ZHANG Jie, et al.
The First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou 730000, China
Abstract:
[Abstract] The bodies of diabetic patients are in internal environment of hyperglycemia for a long time, and when their limb ischemia reperfusion(IR) occurs, the tissues and organs of the diabetic patients are more vulnerable and the damages of their tissues and organs are more serious than those of the non-diabetic patients. This paper reviews the myocardial injury caused by limb IR in patients with diabetes mellitus and its prevention and treatment.
Key words:  Diabetes mellitus  Limb ischemia reperfusion  Myocardial injury  Signal pathway  Energy metabolism disorder