摘要: |
[摘要] 中性粒细胞胞外诱捕网(NETs)是中性粒细胞释放的一种纤维网状结构,其形成过程称为NETosis。近年研究发现,NETs能够促进结直肠癌的增殖、转移和复发,与结直肠癌的预后密切相关。该文对NETs与结直肠癌的关系作一综述,进一步了解NETs在结直肠癌中的作用机制和临床价值。 |
关键词: 中性粒细胞胞外诱捕网 胞外诱捕网形成 结直肠癌 |
DOI:10.3969/j.issn.1674-3806.2023.03.20 |
分类号:R 73 |
基金项目:甘肃省自然科学基金项目(编号:22JR5RA007) |
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Research progress on the relationship between neutrophil extracellular traps and colorectal cancer |
DANG Chun-ping, YUE Hong-yun, ZHANG Bai-hong
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First School of Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, China; Department of Oncology, 940th Hospital of Joint Logistics Support Force of Chinese People′s Liberation Army, Lanzhou 730050, China
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Abstract: |
[Abstract] Neutrophil extracellular traps(NETs) are a fibrous structure released by neutrophils. The formation process is called NETosis. Recent studies have found that NETs can promote the proliferation, metastasis and recurrence of colorectal cancer. They are closely related to the prognosis of colorectal cancer. In this paper, the relationship between NETs and colorectal cancer is systematically reviewed to further understand the mechanism and clinical value of NETs in colorectal cancer. |
Key words: Neutrophil extracellular traps(NETs) NETosis Colorectal cancer |