| 摘要: |
| ［摘要］ 肌肉减少症（简称肌少症）是指与增龄相关的进行性的肌量减少和（或）肌强度下降或肌肉生理功能减退。慢性肾脏病患者由于食欲降低、蛋白摄入减少、慢性炎症、代谢性酸中毒、蛋白质-能量消耗等,继而出现肌肉力量降低、选择性肌肉结构改变和明显的肌肉萎缩，称之为尿毒症肌少症。肌少症严重降低透析患者的生活质量，增加致残率及病死率等。及早发现、诊断及防治肌少症对提高尿毒症患者的生存质量至关重要。该文就尿毒症肌少症的研究进展进行综述。 |
| 关键词: 尿毒症 肌少症 慢性肾脏病 |
| DOI：10.3969/j.issn.1674-3806.2019.06.31 |
| 分类号:R 692 |
| 基金项目: |
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| Research progress of uraemic sarcopenia |
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LI Qiong-xiang, GUO Ai-ling, WENG Min
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Department of Nephrology, the First Affiliated Hospital of Kunming Medical University, Yunnan 650000, China
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| Abstract: |
| ［Abstract］ Sarcopenia is a progressive disease, associated with physiological aging process and defined by the reduction of the muscle mass, strength and/or function. Patients with chronic kidney disease secondarily appear decreased muscle strength, selective muscle structure changes and significant muscle atrophy due to decreased appetite, low protein intake, chronic inflammation, metabolic acidosis and protein-energy wasting are diagnosed with uraemic sarcoprnia. Sarcopenia severely reduces the quality of life of dialysis patients, and increases the patients′ disability rate and death rate. Early detection, diagnosis, prevention and treatment of sarcopenia are essential for improving the quality of life of uraemic patients. The research progress of uraemic sarcopenia is reviewed in this paper. |
| Key words: Uremia Sarcopenia Chronic kidney disease |
