| 摘要: |
| ［摘要］ 目的 探讨肱-踝脉搏波传导速度（baPWV）对冠心病的诊断价值。方法 选取190例受检者根据冠状动脉造影结果分为冠心病组106例和对照组84例，同时将冠心病组进一步分为单支病变组、双支病变组及严重病变组，比较冠心病各组与对照组的baPWV水平。以冠状动脉造影为金标准，绘制ROC曲线评价baPWV值对冠心病的筛选价值。结果 冠心病组baPWV显著高于对照组（P<0.05）。冠心病组单支病变组、双支病变组、严重病变组baPWV值分别为(1 620.13±94.47)cm/s、(1 732.97±84.26)cm/s和（1 913.20±180.75）cm/s，两两比较差异均有统计学意义(P<0.05）。由ROC曲线特征发现，baPWV的最佳截断点为1 535 cm/s，此时约登指数为0.730，灵敏度为83.4%，特异度为88.3%。结论 baPWV对筛选冠心病有一定的价值，并能够预测冠脉病变的严重程度。 |
| 关键词: 脉搏波速度 冠心病 冠状动脉造影 |
| DOI：10.3969/j.issn.1674-3806.2019.07.18 |
| 分类号:R 54 |
| 基金项目: |
|
| Diagnostic value of brachial-ankle pulse wave velocity in coronary heart disease |
|
ZHANG Rong-cheng
|
|
The Second Department of Cardiology, the Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China
|
| Abstract: |
| ［Abstract］ Objective To study the diagnostic value of brachial-ankle pulse wave velocity(baPWV) in coronary heart disease(CHD). Methods One hundred and ninety patients from our hospital were included in this study and the patients were divided into CHD group(n=106) and control group(n=84) according to the result of the coronary angiography(CAG). The CHD group was divided into three sub-groups: single-vessel disease group, double-vessel disease group and severe disease group. The levels of baPWV were compared among the CHD sub-groups and the control group. The outcomes of CAG were taken as the gold standard to evaluate, the efficacy of baPWV in the screening of CHD by drawing ROC curve. Results The level of baPWV in the CHD group was significantly higher than that in the control group(P<0.05). The differences in the baPWV levels between any two groups among the single-vessel disease group(1 620.13±94.47)cm/s, the double-vessel disease group(1 732.97±84.26)cm/s and the severe disease group（1 913.20±180.75）cm/s were significant(P<0.05）. The best cut-off point for screening of CHD was 1 535 cm/s, with the sensitivity being 83.4%, the specificity being 88.3% and Youden′s index being 0.730 from the characteristic of ROC curve. Conclusion The change of baPWV can screen CHD and predict the severity of coronary stenosis. |
| Key words: Pulse wave velocity(PWV) Coronary heart disease(CHD) Coronary angiography(CAG) |
