摘要: |
[摘要] 分化型甲状腺癌发病率逐渐升高,虽然目前甲状腺癌手术治疗方法相对成熟,但预后不良且不能手术的甲状腺癌依然存在,需要寻求其他治疗方法。如能阐明分化型甲状腺癌增生和分化的机制,将有助于找到新的防治靶点。该文就甲状腺癌增生与分化的调节机制作一综述。 |
关键词: 甲状腺癌 增生 分化 |
DOI:10.3969/j.issn.1674-3806.2019.07.28 |
分类号:R 736.1 |
基金项目: |
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The regulatory mechanism of proliferation and differentiation of thyroid cancer |
LIU Zhen-ming, LIU Ping-tao, XIE Zhong-jian
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Institute of Metabolism and Endocrinology of Central South University, Department of Metabolism and Endocrinology of the Second Xiangya Hospital, Central South University, Changsha 410011, China
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Abstract: |
[Abstract] Recently, the incidence of differentiated thyroid cancer is increasing gradually. Although the current treatment of differentiated thyroid cancer is mainly depending on surgery, the thyroid cancer with poor prognosis still relies on other types of therapy. Elucidating the mechanism by which proliferation and differentiation of differentiated thyroid cancer cells are regulated would help identify preventive and therapeutic targets for the disease. The regulatory mechanism of proliferation and differentiation of thyroid cancer is reviewed in this paper. |
Key words: Thyroid cancer Proliferation Differentiation |