| 摘要: |
| ［摘要］ 胃食管反流病(gastroesophageal reflux disease，GERD)是由食管下段括约肌(lower esophageal sphincter，LES)功能不全导致胃、十二指肠内容物反流入食管、口腔或气管引起不适症状和(或)并发症的一种疾病。其主要症状为烧心和反流。目前GERD的主要治疗方法包括药物、内镜及外科手术。但需长期服用质子泵抑制剂，且术后并发症多或疗效不确切。LINX抗反流系统是近年来兴起的一种新型治疗技术，在疗效上具有其独特的优势。该文就LINX抗反流系统治疗GERD的研究进展作一综述。 |
| 关键词: 胃食管反流病 食管下段括约肌 质子泵抑制剂 LINX抗反流系统 |
| DOI：10.3969/j.issn.1674-3806.2019.08.30 |
| 分类号:R 571 |
| 基金项目: |
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| Advances in study on LINX anti-reflux system for treatment of gastroesophageal reflux disease |
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YUE Bin, TANG Xiao-dan.
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Dali University, Yunnan 671000, China
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| Abstract: |
| ［Abstract］ Gastroesophageal reflux disease(GERD) results from incompetency of the lower esophageal sphincter that allows the contents of the stomach and duodenum to reflux into the esophagus, the airways, and the mouth, causing discomfort and/or complications. The main symptoms include heartburn and reflux. At present, the main treatment methods of GERD include medications, endoscopic and surgical treatments. However, most patients have to take proton pump inhibitors for long-term therapy and put up with multiple postoperative complications or poor curative effects. LINX anti-reflux system is a new therapeutic technique emerging in recent years, and has its unique advantages in treatment of GERD. In this paper, we review the advances in the study on LINX anti-reflux system for treatment of GERD. |
| Key words: Gastroesophageal reflux disease（GERD） Lower esophageal sphincter（LES） Proton pump inhibitors(PPIs) LINX anti-reflux system |
