| 摘要: |
| ［摘要］ 目的 分析腹腔镜下行子宫肌瘤剔除术中应用垂体后叶素联合米索前列醇的效果。方法 将2016-06～2017-12收治的80例子宫肌瘤患者随机分为研究组和对照组各40例。研究组术前30 min肛门放置米索前列醇，术中注射垂体后叶素；对照组术中给予缩宫素注射。比较两组手术时间、术中出血量、术中心率、血压及术后血红蛋白、肛门排气时间、体温恢复时间、住院时间及不良反应情况。结果 研究组手术时间、术中出血量均低于对照组，差异有统计学意义（P<0.05），但两组术中心率、收缩压、舒张压比较差异均无统计学意义（P>0.05）。研究组术后血红蛋白水平高于对照组，差异有统计学意义（P<0.05）。两组术后肛门排气时间、体温恢复时间及住院时间比较差异均无统计学意义（P>0.05）。两组术后均无不良反应发生。结论 腹腔镜下行子宫肌瘤剔除术中应用垂体后叶素联合米索前列醇，可显著缩短手术时间，减少术中出血量，值得临床推广应用。 |
| 关键词: 腹腔镜 子宫肌瘤剔除术 垂体后叶素 米索前列醇 |
| DOI：10.3969/j.issn.1674-3806.2019.10.12 |
| 分类号:R 737.33 |
| 基金项目:河池市科学研究与技术开发计划课题（编号：河科转1623-17） |
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| Clinical effect of pituitrin in combination with misoprostol on laparoscopic myomectomy |
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PENG Hua, HE li, OU Wen-mei, et al.
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Department of Gynaecology, the Third People′s Hospital of Hechi City, Guangxi 547000, China
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| Abstract: |
| ［Abstract］ Objective To explore the clinical effect of pituitrin combined with misoprostol on laparoscopic myomectomy. Methods Eighty patients with intramural hysteromyoma were collected from June 2016 to December 2017 and were randomly divided into the observation group(n=40) and the control group(n=40). In the observation group, misoprostol was placed in the anus 30 min before operation, and pituitrin was injected intraoperatively. In the control group, oxytocin was injected intraoperatively. The operative time, intraoperative blood loss, intraoperative heart rate, blood pressure, and postoperative hemoglobin, anal exhaust time, recovery time of body temperature, hospitalization time and adverse reactions were compared between the two groups. Results The operation time in the observation group was significantly shorter than that in the control group(P<0.05). The intraoperative blood loss of the observation group was significantly less than that of the control group(P<0.05). There were no significant differences in the heart rate, systolic pressure and diastolic pressure between the two groups（P>0.05）. The level of hemoglobin in the observation group was significantly higher than that of the control group（P<0.05）. There were no significant differences in the postoperative anus exhaust time, recovery time of body temperature and hospitalization time between the two groups（P>0.05）. No adverse reactions occurred in the two groups after operation. Conclusion Pituitrin in combination with misoprostol can significantly shorten the operative time and reduce the intraoperative blood loss during laparoscopic myomectomy, which is worthy of clinical application. |
| Key words: Laparoscope Myomectomy Pituitrin Misoprostol |
