引用本文:李自涛,马志军,刘 震,沈国双.原发性甲状旁腺功能亢进症18例外科治疗及误诊分析[J].中国临床新医学,2019,12(10):1098-1102.
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原发性甲状旁腺功能亢进症18例外科治疗及误诊分析
李自涛,马志军,刘 震,沈国双
810001 西宁,青海大学附属医院乳腺甲状腺科
摘要:
[摘要] 目的 分析原发性甲状旁腺功能亢进症(PHPT)的外科治疗经验及误诊情况。方法 回顾性分析2013-01~2016-12青海大学附属医院收治的18例PHPT患者的临床表现、实验室检查、影像学检查、治疗方式及随访结果。结果 18例患者中,8例行手术治疗,术后随访2~5年,无复发及再次手术者;10例仍在观察随访中,未行药物治疗,症状没有明显加重,生活质量可。结论 大部分PHPT是由甲状旁腺瘤引起,目前手术是主要的治疗手段。仍有很大一部分PHPT患者没有任何不适症状,或者症状不典型,这部分PHPT患者手术及药物治疗指征还不明确。
关键词:  原发性甲状旁腺功能亢进症  甲状旁腺瘤  诊断  外科治疗  误诊分析
DOI:10.3969/j.issn.1674-3806.2019.10.14
分类号:R 582+.2
基金项目:
Surgical treatment and misdiagnosis of 18 cases of primary hyperparathyroidism
LI Zi-tao, MA Zhi-jun, LIU Zhen, et al.
Department of Breast and Thyroid Surgery, Affiliated Hospital of Qinghai University, Xining 810001, China
Abstract:
[Abstract] Objective To summarize the surgical treatment experience and misdiagnosis analysis of primary hyperparathyroidism(PHPT). Methods Eighteen PHPT patients admitted to the Affiliated Hospital of Qinghai University from January 2013 to December 2016 were collected, and their clinical manifestations, laboratory examination, imaging examination, treatment methods and follow-up results were retrospectively analyzed. Results Of the 18 patients, 8 underwent surgical treatment, and the patients were followed up for 2~5 years. After the follow-up, no recurrence and reoperation occurred. The other 10 patients were not treated with any drugs during the follow-up, but their symptoms were not obviously aggravated and the quality of life was still good. Conclusion Most patients with PHPT are caused by parathyroid adenoma, and surgery is still the main treatment. A large number of PHPT patients still have no any symptoms, or their symptoms are not typical, among whom the indications for surgery and medication are still unclear.
Key words:  Primary hyperparathyroidism(PHPT)  Parathyroid adenoma  Diagnosis  Surgical treatment  Misdiagnosis analysis