| 摘要: |
| ［摘要］ 右美托咪定（dexmedetomidine，DEX）是一种高选择性α2型肾上腺素能受体激动剂，临床作用广泛。该文就DEX药理及其对器官保护的作用作一综述，重点阐述临床应用对机体神经系统及心、肺、肝、肾器官的保护作用的研究进展。 |
| 关键词: 右美托咪定 器官保护 药理作用 |
| DOI：10.3969/j.issn.1674-3806.2020.10.27 |
| 分类号:R 614 |
| 基金项目:国家自然科学基金资助项目（编号：81360020）；广西医疗卫生适宜技术开发与推广应用项目（编号：S2019074）；南宁市青秀区科技计划项目（编号：2019033）；广西卫健委科研项目（编号：Z20180699，Z20170363） |
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| Research progress in pharmacological action and organ protection of dexmedetomidine |
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GONG Zheng, WEI Hui-jun, LI Jun, et al.
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Department of Anesthesiology, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Dexmedetomidine(DEX) is a highly selective α2 adrenergic receptor agonist with a wide range of clinical effects. In this paper, the pharmacological action and organ protective effect of DEX are reviewed, with emphasis on the progress of its clinical application in the protection of nervous system and heart, lung, liver and kidney organs. |
| Key words: Dexmedetomidine(DEX) Organ protection Pharmacological action |
