| 摘要: |
| ［摘要］ 目的 探讨腹膜播散性平滑肌瘤病(LPD)的临床病理学特征、诊断及鉴别诊断。方法 回顾性分析4例LPD患者的临床病理学特征、组织学形态及免疫表型并复习相关文献。结果 4例均为女性，年龄32～51岁。镜检：肿瘤由梭形细胞组成，呈编织状排列，胞浆红染，核呈杆状，细胞大小较一致，无核分裂象。免疫表型：瘤细胞表达平滑肌肌动蛋白(SMA)、结蛋白(desmin)、Ki-67，而CD117、CD34、S-100、DOG-1均为阴性。结论 LPD是一种罕见的良性肿瘤，预后良好，诊断主要依赖其组织病理学特征及免疫表型。 |
| 关键词: 腹膜播散性平滑肌瘤病 免疫组织化学 鉴别诊断 |
| DOI：10.3969/j.issn.1674-3806.2020.12.17 |
| 分类号:R 735.4 |
| 基金项目: |
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| Leiomyomatosis peritonealis disseminata: a clinicopathological feature analysis of 4 cases and review of literatures |
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WU Ying-ying, DING Li, YANG Rui-xue, et al.
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Department of Pathology, the First Affiliated Hospital of Bengbu Medical College, Anhui 233000, China
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| Abstract: |
| ［Abstract］ Objective To investigate the clinicopathological features, diagnosis and differential diagnosis of leiomyomatosis peritonealis disseminata(LPD). Methods The clinicopathological features, histological morphology and immunophenotype of 4 patients with LPD were retrospectively analyzed and the relevant literatures were reviewed. Results All of the 4 cases were female, aged 32～51 years. Microscopy: The tumors were consisted of relatively uniform spindle cells in an interlacing arrangement, cytoplasmic red staining, rod-shaped nuclei and rare mitosis. Immunophenotype: The tumor cells expressed smooth muscle actin(SMA), desmin and Ki-67, while CD117, CD34, S-100 and DOG-1 were all negative. Conclusion LPD is a rare benign tumor with a good prognosis. Its diagnosis mainly depends on its histopathological characteristics and immunophenotype. |
| Key words: Leiomyomatosis peritonealis disseminata(LPD) Immunohistochemistry Differential diagnosis |
