| 摘要: |
| ［摘要］ 肺炎链球菌是5岁以下儿童死亡的主要病原体，也是重症肺炎和坏死性肺炎最常见病原体。肺炎链球菌对常用抗菌药物特别是大环内酯类耐药日趋严重，但病原学检测仍是个难题，如传统的培养分离法、现代的分子生物学技术尚不能满足临床快捷、准确、安全、价廉的要求。如何准确识别肺炎链球菌，合理应用抗菌药物，减少耐药性以及推广肺炎链球菌疫苗是儿科医师面临的一大挑战。该文对肺炎链球菌肺炎临床表现、诊断、治疗及预防进展进行综述。 |
| 关键词: 肺炎链球菌肺炎 儿童 诊断 病原学 治疗 预防 |
| DOI：10.3969/j.issn.1674-3806.2021.03.04 |
| 分类号:R 725.6 |
| 基金项目:广西卫健委科研课题（编号：Z20170360） |
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| Strategies for diagnosis, prevention and treatment of Streptococcus pneumoniae pneumonia in children |
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WEN Zhi-hong
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Department of Paediatrics, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Streptococcus pneumoniae is the main pathogen causing death in children under 5 years old, and is also the most common pathogen of severe pneumonia and necrotizing pneumonia. The resistance of Streptococcus pneumoniae to commonly used antibacterial agents, especially macrolides, is becoming more and more serious, but the pathogen detection is still a problem: traditional bacterial culture and isolation methods and modern molecular biology technology can not meet the rapid, accurate, safe and inexpensive requirements in clinical practice. How to identify Streptococcus pneumoniae accurately, use antimicrobial agents rationally, reduce drug resistance and popularize Streptococcus pneumoniae vaccination is a major challenge for pediatricians. In this paper, the progress of clinical manifestation, diagnosis, treatment and prevention of Streptococcus pneumoniae pneumonia is reviewed. |
| Key words: Streptococcus pneumoniae pneumonia Children Diagnosis Aetiology Treatment Prevention |
