引用本文:谢 思,黎乐群.非酒精性脂肪性肝病相关性肝细胞癌治疗的研究进展[J].中国临床新医学,2022,15(2):105-109.
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非酒精性脂肪性肝病相关性肝细胞癌治疗的研究进展
谢 思,黎乐群
530021 南宁,广西医科大学附属肿瘤医院肝胆外科(谢 思,黎乐群);530021 南宁,广西壮族自治区人民医院胃肠疝肠瘘外科(谢 思)
摘要:
[摘要] 肝细胞癌(HCC)发病率高,乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)感染是HCC的主要病因。近年来,肥胖、2型糖尿病等代谢疾病的流行加速了非酒精性脂肪性肝病(NAFLD)的发生,导致NAFLD相关性HCC(NAFLD-HCC)的发生也逐年递增。但NAFLD-HCC与病毒相关性HCC是否有相似的发病机制、预防、监测以及治疗策略尚未清晰。该文就以上问题进行综述,为NAFLD-HCC的防治提供参考。
关键词:  肝细胞癌  非酒精性脂肪性肝病  治疗  总生存率
DOI:10.3969/j.issn.1674-3806.2022.02.03
分类号:R 735.7
基金项目:国家自然科学基金项目(编号:81960534)
Research progress in the treatment of non-alcoholic fatty liver disease-related hepatocellular carcinoma
XIE Si, LI Le-qun
Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning 530021, China
Abstract:
[Abstract] The incidence of hepatocellular carcinoma(HCC) is high, and hepatitis B virus(HBV) and hepatitis C virus(HCV) infections are the main causes of HCC. In recent years, the prevalence of metabolic diseases such as obesity and type 2 diabetes has accelerated the occurrence of non-alcoholic fatty liver disease(NAFLD), resulting in the occurrence of NAFLD-related HCC(NAFLD-HCC) increasing year by year. However, it remains unclear whether NAFLD-HCC and virus-related HCC have similar pathogenesis, prevention, surveillance and treatment strategies. This paper reviews the above problems and provides reference for the prevention and treatment of NAFLD-HCC.
Key words:  Hepatocellular carcinoma(HCC)  Non-alcoholic fatty liver disease(NAFLD)  Treatment  Overall survival rate