| 摘要: |
| ［摘要］ 目的 分析腔内介入治疗TASC-Ⅱ分级为C、D级下肢动脉硬化闭塞症（ASO）的临床疗效。方法 收集2017年1月至2019年8月于安徽医科大学附属合肥医院介入血管疼痛科就诊并接受腔内介入治疗的52例下肢ASO患者（共57条患肢）的临床资料。分析患者手术成功率、并发症发生率、通畅率和保肢率等情况。结果 52例患者（57条患肢）共计行腔内介入治疗62次。其中2条患肢反复尝试后未能成功开通闭塞段，1条患肢因术中患者出现急性左心功能衰竭中止手术。3条患肢转骨科行截肢治疗，手术成功率为94.74%（54/57）。共计出现围术期并发症2例（3.85%），其中穿刺部位血肿1例，术后患肢出现缺血再灌注损伤1例，无围术期死亡病例。术后1个月足背动脉和胫后动脉踝肱指数(ABI)均较术前显著增加（P<0.05）。术后1、3、6、12、18、24个月，患肢一期通畅率分别为100.00%、97.96%、93.88%、78.72%、77.78%、68.18%。术后12个月和24个月的二期通畅率分别为95.35%和94.44%。术后12个月和24个月的保肢率分别为95.74%、90.90%。结论 对于病变较长且较为严重的下肢ASO,腔内介入治疗是一种安全、有效的治疗方式。 |
| 关键词: 下肢 动脉硬化闭塞症 腔内介入治疗 临床疗效 |
| DOI：10.3969/j.issn.1674-3806.2022.03.09 |
| 分类号:R 605 |
| 基金项目:安徽省中央引导地方科技惠民示范项目（编号：202007d07050004） |
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| Analysis of the clinical effect of intracavitary interventional therapy on patients with TASC-Ⅱ grade C and grade D lower extremity arteriosclerosis obliterans |
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LI Jing, YIN Shi-wu, PAN Sheng-quan, et al.
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Department of Interventional Vessel and Pain, Hefei Hospital Affiliated to Anhui Medical University, Hefei 230011, China
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| Abstract: |
| ［Abstract］ Objective To analyse the clinical effect of intracavitary interventional therapy on patients with Trans-Atlantic Inter-Society Consensus(TASC)-Ⅱ grade C and grade D lower extremity arteriosclerosis obliterans(ASO). Methods The clinical data of 52 patients with lower extremity ASO(57 affected limbs) who were treated in the Department of Interventional Vessel and Pain, Hefei Hospital Affiliated to Anhui Medical University and received intracavitary interventional therapy from January 2017 to August 2019 were collected. The surgical success rate, complication rate, patency rate and limb salvage rate of the patients were analyzed. Results Fifty-two patients(57 affected limbs) underwent 62 times of intracavitary interventional therapy. Among the 57 affected limbs, the occluded segments of 2 affected limbs failed to open successfully after repeated attempts; the operation on 1 affected limb was discontinued due to acute left heart failure in the patient during the operation; 3 affected limbs were transferred to the orthopedics department for amputation, and the success rate of the operation was 94.74%(54/57). Perioperative complications occurred in 2 cases(3.85%), including 1 case of hematoma at the puncture site and 1 case of postoperative ischemia-reperfusion injury in the affected limb, and no perioperative death. The levels of ankle-brachial index(ABI) of the dorsal pedis artery and the posterior tibial artery one month after operation were significantly higher than those before operation(P<0.05). The first-stage patency rates of the affected limbs were 100.00%, 97.96%, 93.88%, 78.72%, 77.78% and 68.18% 1, 3, 6, 12, 18 and 24 months after operation, respectively. The second-stage patency rates 12 and 24 months after operation were 95.35% and 94.44%, respectively. The limb salvage rates 12 and 24 months after operation were 95.74% and 90.90%, respectively. Conclusion Intracavitary interventional therapy is a safe and effective treatment for lower extremity ASO with longer and more severe lesions. |
| Key words: Lower extremities Arteriosclerosis obliterans(ASO) Intracavitary interventional therapy Clinical effect |
