摘要: |
[摘要] 代谢相关脂肪性肝病(MAFLD)对人类健康所构成的威胁不容忽视,现代医学关于MAFLD的发病机制的探讨较多,该文回顾了MAFLD的发病机制及其与肠道真菌群的关系,并讨论了肠道真菌群可能影响疾病进展的机制。控制肠道真菌群的策略可能被开发用于治疗或预防肝脏疾病。 |
关键词: 代谢相关脂肪性肝病 发病机制 肠道真菌群 肠道细菌群 |
DOI:10.3969/j.issn.1674-3806.2022.08.21 |
分类号:R 575.1 |
基金项目:国家自然科学基金地区基金项目(编号:81860821) |
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Research progress on the pathogenesis of metabolic-associated fatty liver disease and its relationship with intestinal fungal community |
XIE Jiao-jiao, WANG Li, HE Yan-fang, et al.
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First School of Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, China
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Abstract: |
[Abstract] The threat of metabolic-associated fatty liver disease(MAFLD) to human health cannot be ignored. There are many discussions about the pathogenesis of MAFLD in modern medicine. In this paper, we review the pathogenesis of MAFLD and its relationship with intestinal fungal community, and discuss the mechanisms by which the intestinal fungal community may influence the disease progression. Strategies to control the intestinal fungal community may be developed to treat or prevent liver disease. |
Key words: Metabolic-associated fatty liver disease(MAFLD) Pathogenesis Intestinal fungal community Intestinal bacterial flora |