| 引用本文: | 张洪剑,沈红健,杨鹏飞,邢鹏飞,张磊,张永巍,刘建民.高龄急性前循环大血管闭塞缺血性卒中患者血管内治疗预后的影响因素分析[J].中国临床新医学,0,():-. |
| ZHANG Hong-jian,SHEN Hong-jian,YANG Peng-fei,XING Peng-fei,ZHANG Lei,ZHANG Yong-wei,LIU Jian-ming.高龄急性前循环大血管闭塞缺血性卒中患者血管内治疗预后的影响因素分析[J].中国临床新医学,0,():-. |
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| 摘要: |
| 目的 分析高龄急性大血管闭塞缺血性卒中(AIS-LVO)患者血管内治疗预后的影响因素。方法 选择2017年1月至2018年12月在海军军医大学(第二军医大学)长海医院脑血管病中心接受血管内治疗的AIS-LVO高龄患者66例,以治疗后3个月改良 Rankin 量表(mRS)评分作为预后评价指标,mRS评分≤2分的患者为预后良好组(20例),3～6 分为预后不良组(46例)。分析两组患者的危险因素、神经功能状况、影像学特征等指标,采用多因素 logistic 回归分析影响高龄患者血管内治疗预后的影响因素。结果 血管内治疗后3个月预后良好率为30.3%(20/66),预后良好组和预后不良组患者的基线NIHSS评分、核心梗死体积差异有统计学意义(P<0.05)。多因素logistic回归分析表明核心梗死>20ml[比值比＝3.453,95% 置信区间：1.015～11.744,P＝0.047]为AIS-LVO高龄患者血管内治疗预后不良的危险因素。 结论 核心梗死是影响AIS-LVO高龄患者血管内治疗预后的独立危险因素,核心梗死体积越大,预后越差。 |
| 关键词: 急性缺血性脑卒中 大血管闭塞 预后 血管内治疗 核心梗死 |
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| 基金项目:] 上海市科技创新行动计划重点项目(14401970304). Supported by Key Program of Technology and Innovation Action Plan of Shanghai (14401970304). |
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| Prognostic factors of acute ischemic stroke patients with large vessel occlusions aged ≥ 80#$NBSyears treated with endovascular therapy |
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ZHANG Hong-jian, SHEN Hong-jian, YANG Peng-fei, XING Peng-fei, ZHANG Lei, ZHANG Yong-wei, LIU Jian-ming
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Stroke Center,Changhai Hospital,Navy Medical University Second Military Medical University
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| Abstract: |
| Objective To explore the prognostic influencing factors of acute ischemic stroke patients with large vessel occlusions(AIS-LVO) aged ≥80Syears treated with endovascular therapy. Methods From January 2017 to December 2018, 66 elderly patients with AIS-LVO underwent endovascular therapy in Stroke Center of Changhai Hospital of Navy Medical University (Second Military Medical University) were included in this study. The modified Rankin scale (mRS) score at 3 months after therapy was used as an prognostic indicator, the patients with mRS score≤2 were good prognosis group (n＝20) and the patients with mRS score being 3-6 were poor prognosis group (n＝46). The The risk factors, neurological function and imaging data of patients between two groups were compared. Multivariate logistic regression was used to analyze the influencing factors on the prognosis of elderly patients undergoing endovascular therapy. Results The good prognosis rate was 30.3% (20/66) at 3 months. The baseline NIHSS score and core infarction volume of patients had significant differences between the good and poor prognosis groups (P< 0.05). Multivariate logistic regression analysis showed that core necrosis > 20 ml [ratio = 3.453, 95% confidence interval: 1.015-11.744, P = 0.047] was a risk factor for poor prognosis of endovascular therapy in elderly patients with AIS-LVO. Conclusion Core infarction is an independent risk factor affecting the prognosis of endovascular therapy in elderly patients with AIS-LVO. The larger the volume of core infarction, the worse the prognosis. |
| Key words: acute ischemic stroke large vessel occlusions prognosis endovascular therapy core infarction |
