| 引用本文: | 韦红兰,林忠,吴秀芬,陈武玲,巫晓霞.延长放置COOK球囊在治疗中重度宫腔粘连的疗效及安全性分析[J].中国临床新医学,0,():-. |
| WEI Honglan,LIN Zhong,WU Xiufen,CHEN Wuling,WU Xiaoxia.延长放置COOK球囊在治疗中重度宫腔粘连的疗效及安全性分析[J].中国临床新医学,0,():-. |
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| 摘要: |
| 目的 探讨延长放置COOK球囊子宫支架在中重度宫腔粘连分离术后预防再次粘连的临床治疗效果及安全性。方法 选择2016-01～2018-12在该院诊断为中重度宫腔粘连并行粘连分离术的患者，共210例，采用随机数字表法将其分为对照组与试验组，每组105例。对照组在予宫腔镜宫腔粘连分离术后放置COOK球囊，1周后取出。试验组在予宫腔镜宫腔粘连分离术后放置COOK球囊，1周后剪球囊尾管放出球囊内液体，留置球囊支架，术后第2次月经干净后取出。比较两组术后宫腔粘连、月经恢复、并发症的发生情况。结果 对照组术后第1个月经改善率为72.38%，试验组为77.14%，两组差异无统计学意义（p＞0.05）；但两组术后第2个月、第3个月及第6个月试验组的月经改善率高于对照组，差异有统计学意义（p＜0.05）。对照组宫腔粘连改善有效率为76.19%，试验组为87.62%，两组差异有统计学意义（p＜0.05）。对照组术后无并发症情况发生，试验组术后有10例（9.52%）并发症，两组并发症发生率比较差异有统计学意义（p＜0.05）。结论 COOK宫腔球囊延长放置可以改善宫腔粘连，改善月经量，但延长放置COOK球囊存在一定的风险，经处理后可治愈，是相对安全的，临床工作中仍需严密观察及随访。 |
| 关键词: COOK球囊 延长放置 宫腔粘连 宫腔粘连分离术。 |
| DOI： |
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| 基金项目:广西壮族自治区卫生厅自筹经费科研课题(No：Z20170493) |
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| The efficacy and safety analysis of prolonged placement of COOK balloon in the treatment of moderate to severe intrauterine adhesions |
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WEI Honglan, LIN Zhong, WU Xiufen, CHEN Wuling, WU Xiaoxia
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Department of gynaecology,Liuzhou Maternal and Child Health Care Hospital,Guang Xi,545001
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| Abstract: |
| To assess the clinical efficacy and safety of prolonged placement of COOK balloon uterine stent in prevention of adhesion reformation after hysteroscopic adhesiolysis inpatients with moderate to severe intrauterine adhesions. Methods：A total of 210 patients diagnosed with moderate to severe intrauterine adhesions, hysteroscopic adhesiolysis was performed in the hospital were selected from January 2016 to December 2018, and they were divided into the control group and the experimental group by the method of random number table, with 105 patients in each group. In the control group, COOK balloon was placed after transcervical resection of adhesions and removed 1 week later. The experimental group， COOK balloon was placed after hysteroscopic adhesiolysi, after 1 week, the scissoring balloon tail tube released balloon fluid, the balloon stent was indwelling and removed after the 2nd menstruation. The incidence of intrauterine adhesions, menstrual recovery and complications were compared between the two groups. Results：The menstruation improvement rate in the first postoperative period was 72.38% in the control group and 77.14% in the experimental group, the difference was not statistically significant (P>0.05). However, the menstrual improvement rate of the experimental group was higher than that of the control group at 2, 3 and 6 months after surgery,the difference was statistically significant(P<0.05). The effective rate of intrauterine adhesions improvement was 76.19% in the control group and 87.62% in the experimental group, the difference was statistically significant (p<0.05). There were no postoperative complications in the control group and 10 cases (9.52%) in the experimental group. The difference in the incidence of postoperative complications between the two groups was statistically significant (p<0.05). Conclusion：Prolonged placement of COOK uterine balloon can improve intrauterine adhesions and menstrual flow, but prolonged placement of COOK balloon has certain risks, which can be cured after treatment and is relatively safe. Clinical work still requires close observation and follow-up. |
| Key words: COOK balloon,extended placement,Intrauterine adhesions,Hysteroscopic adhesiolysis. |
