摘要: |
目的 比较药物涂层球囊和药物洗脱支架在冠状动脉原位病变的应用效果。方法 选取郑州大学第五附属医院心血管内科2016年7月至2018年7月收治的冠心病患者110例,按照治疗方式的不同随机分成药物涂层球囊(DCB)组55例和药物洗脱支架(DES)组55例。比较两组9个月后靶病变血管血运重建率(TLR)、主要心脏不良事件(MACE)及定量冠状动脉造影(QCA)结果。结果 PCI后9个月,两组患者TLR率比较,差异无统计学意义(P>0.05),DCB组的晚期管腔丢失小于DES组,差异有统计学意义(P<0.05)。结论 DCB可减小晚期管腔丢失,且在TLR方面与DES无差异,在冠状动脉原位病变中有较高的临床应用价值。 |
关键词: 药物球囊 原位病变 药物支架 冠心病 |
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Comparison of drug-coated balloon#$NBS#$NBSand drug-eluting stent for de novo lesions#$NBSin#$NBScoronary artery disease |
tongjinghuang
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The Fifth Affiliated Hospital of Zhengzhou University
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Abstract: |
Objective To compare drug-coated balloonSSand drug-eluting stent for de novo lesionsSinScoronary artery disease.Methods A total of 110 patients with coronary heart disease treated by percutaneous coronary intervention in the Fifth Affiliated Hospital of Zhengzhou University from July 2016 to July 2018 were selected as the subjects,and randomly divided into drug balloon group (n=55) and drug-eluting stent group (n=55) according to different treatment methods.The target lesion vascular revascularization rate (TLR), major cardiac adverse events (MACE), and quantitative coronary angiography (QCA) were compared after 9 months. Results: At 9 months after PCI, there was no significant difference in TLR between the two groups (P>0.05). The late lumen loss in the DCB group was lower than that in the DES group, and the difference was statistically significant (P<0.05). Conclusion: The DCB can reduce late lumen loss, and there is no difference in TLR between the two groups, which has high application value for de novo lesions in coronary artery disease. |
Key words: drug-coated balloon de-nove lesions drug-eluting stent coronary heart disease |