引用本文:蒙志好,蓝珂,窦艳云,左勇,陆雪萍,龚世江.HIV抗体不确定37例随访及治疗分析[J].中国临床新医学,0,():-.
mengzhihao.HIV抗体不确定37例随访及治疗分析[J].中国临床新医学,0,():-.
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HIV抗体不确定37例随访及治疗分析
蒙志好, 蓝珂, 窦艳云, 左勇, 陆雪萍, 龚世江
广西壮族自治区龙潭医院
摘要:
目的 探讨HIV-1抗体不确定者追踪随访结果，为快速诊治提供依据。方法 对2019-01~2020-06在广西龙潭医院就诊的37例HIV-1抗体不确定者的临床资料进行整理，分析其诊断和治疗经过，归纳其临床特点。结果 37例HIV-1抗体初筛阳性者，首次确认试验均不确定，经过追踪随访及核酸检测，证实21例为HIV-1感染，15例为HIV-1以外的其它疾病，1例未复诊。21例HIV/AIDS中合并机会性感染11例，无症状10例。13例进行了抗病毒治疗，半年后CD4+T淋巴细胞平均升高234/mm3，病毒抑制率92.31%。结论 抗体检测仍是诊断HIV-1感染的主要方法，抗体不确定给HIV/AIDS诊断增加了难度，及时随访并进行确证试验或核酸检测，为早诊断、早治疗提供证据。
关键词:  人类免疫缺陷病毒  艾滋病  核酸检测  早期诊断  抗病毒治疗
DOI：
分类号:
基金项目:] 国家科技重大专项(2017ZX10202101-002-002,2017ZX10202101-001-006),自治区卫健委重点课题(重2011067),自治区卫健委自筹经费课题(Z2008023)。
The follow-up and treatment analysis for 37 patients with uncertain HIV antibody
mengzhihao
Longtan Hospital of Guangxi Zhuang Autonomous Region
Abstract:
Objective:To explore the follow-up results of people with uncertain HIV antibodies，and provide bases for rapid diagnosis and treatment.. Methods:To finishing clinical data of 37 patients with uncertain HIV antibodies who were treated in our hospital from January 2019 to June 2020.We needed to analyze their diagnosis and treatment, and summarized their clinical characteristics. Results:The 37 cases of HIV antibody initial screening positive, the first confirmation testing was uncertain.After follow-up and nucleic acid testing, 21 cases were confirmed to be HIV infection, 15 cases were other diseases other than HIV, and 1 case did not follow up.Among 21 cases of HIV/AIDS, 11 cases were combined with opportunistic infections and the other 10 cases were asymptomatic.13 cases of them received antiviral treatment, and CD4+ T lymphocytes increased by an average of 234/mm3 after half a year, and the virus inhibition rate was 92.31%. Conclusion:Antibody testing is still the main method for diagnosing HIV infection, but the results of HIV antibody testing show uncertainty, which makes the diagnosis of HIV/AIDS more difficult.Timely follow-up and confirmatory tests or nucleic acid testing provide evidence for early diagnosis and early treatment of HIV-infected patients.
Key words:  human immunodeficiency virus  AIDS  nucleic acid amplification testing  early diagnosis  antiviral therapy