引用本文:黄兰诚,周凯,冯梦龙.耳聋基因突变与人工耳蜗术后疗效的相关性研究进展[J].中国临床新医学,0,():-.
HUANG Lan-cheng,ZHOU Kai,FENG Meng-long.耳聋基因突变与人工耳蜗术后疗效的相关性研究进展[J].中国临床新医学,0,():-.
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耳聋基因突变与人工耳蜗术后疗效的相关性研究进展
黄兰诚, 周凯, 冯梦龙
广西壮族自治区人民医院
摘要:
人工耳蜗(Cochlear implantat,CI)自投入使用以来,一直是双耳重度和极重度感音神经性聋患者获得听力的最有效方式。但少部分先天性耳聋患者行人工耳蜗植入术后,经过听力言语功能训练仍未能获得满意的术后效果。近年来,随着基因检测技术的发展,耳聋基因作为先天性耳聋患者病因学研究取得初步成效,其对人工耳蜗术后疗效的影响也被广泛研究。本文就耳聋基因突变与人工耳蜗术后疗效的相关性研究进行综述。
关键词:  耳聋基因、人工耳蜗、术后疗效
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基金项目:广西科技厅重点研发项目（编号：桂科AB17292089）；广西医疗卫生适宜技术开发与推广应用项目（编号：S2017 078）；广西卫健委科研课题（编号：Z20170366）
Progress in the study of the relationship between gene mutation and the curative effect of Cochlear Implantation
HUANG Lan-cheng, ZHOU Kai, FENG Meng-long
Department of Otolaryngology,Head and Neck Surgery,the People’s Hospital of Guangxi Zhuang Autonomous Region
Abstract:
Cochlear implant (CI) has been the most effective way to treat severe and extremely severe sensorineural hearing loss since its application. However, a small number of congenital deafness patients after cochlear implantation, they still failed to obtain satisfactory postoperative results after hearing and speech function training. In recent years, with the development of gene detection technology,the etiology of deafness gene as a congenital deafness patient has achieved preliminary results, and its influence on the postoperative effect of cochlear implantation has also been widely studied. This article reviews the relationship between gene mutation and the curative effect of cochlear Implantation.
Key words:  Deafness  gene, Cochlear  implant, Postoperative  effect