| 引用本文: | 温志红,唐慧荷,王浜琴,刘兴夏,陆春久,张迪雯.一起广西新型冠状病毒肺炎家庭聚集性疫情流行病学和临床分析[J].中国临床新医学,0,():-. |
| .一起广西新型冠状病毒肺炎家庭聚集性疫情流行病学和临床分析[J].中国临床新医学,0,():-. |
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| 摘要: |
| [摘要] 目的 探讨一起新型冠状病毒肺炎（COVID-19）家庭聚集性疫情的流行病学及临床特征，为进一步防控工作提供佐证。方法（1）流行病学调查：通过向患者本人、家属以及其他知情人员（医务人员）进行电话、面对面访谈，收集所有病例暴露史、家庭聚集性发病情况、医学/家庭隔离情况。（2）临床资料收集：通过查阅病历、向患者本人及家属询问病史，收集患者一般情况、临床症状、体征、实验室检查、影像学结果、治疗方案、疾病转归及随访近期预后。结果（1）1个家庭共10例COVID-19确诊病例，有与武汉疫区确诊COVID-19指示病例直接或间接密切接触、共同生活流行病学特征。（2）11例COVID-19确诊病例均无重症患者，儿童临床表现轻且不典型。（3）经治疗达出院标准COVID-19患者出院后有4例新型冠状病毒（SARS-CoV-2）核酸复阳，1例成人症状轻微，3例儿童均无症状。结论（1）聚集性发病是本次疫情的重要流行特征，家庭内密切接触是儿童COVID-19感染主要方式。（2）出院后SARS-CoV-2核酸复阳性并不能用于评估疾病严重程度。 |
| 关键词: 新型冠状病毒肺炎，家庭聚集，流行病学，临床特征 |
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| To analyze the epidemiological and clinical characteristics of a family cluster with COVID-9 |
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he People’s Hospital of Guangxi Zhuang Autonomous Region
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| Abstract: |
| [Objective] The aim of this study was to explore the epidemiological and clinical features of a COVID-19 family cluster. These data may benefit to provide evidence for further prevention and control efforts.
[Methods](1) Epidemiological investigation: Telephone and face-to-face interviews were conducted with the patient, patient’s family and other informed people (medical staff), collected exposure history of all cases , incidence of familial aggregation and medical/family isolation. (2) Clinical data collection: The general information, clinical symptoms, signs, laboratory examination, imaging results, treatment plan, disease outcome and follow-up of short-term prognosis of the patients were collected by consulting the medical records and acquiring the medical history of the patients and their family members.
[Results]A total of 10 COVID-19 patients from the same family were included.Direct or secondary close contact with the index case. None of the 11 patients were critical ill, and the clinical manifestations of the children cases were mild and atypical.After treatment, 4 patients who met discharge criteria for COVID-19 were retested positive for novel Coronavirus nucleic acid（SARS-CoV-2）, of which, 1 adult had mild symptoms and 3 children had no symptoms.
[Conclusion]This study demonstrates a significant characteristic of cluster in COVID-19 and emphasizes that the foremost way of children infection is close contact within the family.Post-discharge SARS-CoV-2 nucleic acid re-positivity can not used to assess the severity of the disease. |
| Key words: Coronavirus disease 2019 Family clusters Epidemiology Clinical characteristics |
