| 引用本文: | 黄光坚,覃惠洵,陈红,杨明秀,张皆德,付琳,唐毅斯,覃彬,覃城.脑侧支循环对静脉溶栓患者预后的影响[J].中国临床新医学,0,():-. |
| Huang Guang-jian,Qin Hui-xun,Chen Hong,Yang Ming-xiu,Zhang Jie-de,Fu Lin,Tang Yi-si,Qin Bin,Qin Cheng.脑侧支循环对静脉溶栓患者预后的影响[J].中国临床新医学,0,():-. |
|
| |
|
|
| 本文已被：浏览 150次 下载 0次 |
|
|
|
| 脑侧支循环对静脉溶栓患者预后的影响 |
|
黄光坚, 覃惠洵, 陈红, 杨明秀, 张皆德, 付琳, 唐毅斯, 覃彬, 覃城
|
|
广西柳州市人民医院
|
|
| 摘要: |
| 目的S 利用DSA检查评估脑侧支循环状态并分析其对静脉溶栓的急性脑梗死患者预后的影响。方法S 收集分析2018年1月至2019年12月在我院卒中中心登记的接受静脉溶栓治疗并行脑血管造影DSA检查的121例患者的临床资料,按DSA结果将患者分为侧支循环代偿良好组(53例,3~4级)与侧支循环代偿不良组(68例,0~2级)。比较两组患者头颅磁共振DWI片上脑梗死体积、NIHSS评分、ADL评分、脑出血发生率等。结果S侧支循环代偿良好组脑梗死体积明显小于侧支循环代偿不良组(P﹤0.05),且侧支循环代偿良好组溶栓后出血并发症也较低(P﹤0.05)。与溶栓前比较,两组患者溶栓后7天、3个月及6个月的NIHSS评分均明显降低(均p＜0.05)；两组患者溶栓后7天、3个月及6个月的ADL评分均明显提高,(均p＜0.05)。与侧支循环代偿不良组比较,侧支循环代偿良好组患者溶栓前、溶栓后7天、3个月及6个月的NIHSS评分均明显低于代偿不良组,(均p＜0.05)；同时,代偿良好组溶栓前及溶栓后7天、3个月及6个月的ADL评分均明显高于代偿不良组(均P＜0.05)。结论S 脑侧支循环对急性脑梗死患者的静脉溶栓疗效及预后有重要影响,良好的脑侧支循环可显著改善患者的预后。 |
| 关键词: 急性缺血性卒中 侧支循环 静脉溶栓 数字减影血管造影 |
| DOI： |
| 分类号: |
| 基金项目:广西壮族自治区卫计委科研课题(Z 20180284) |
|
| Effect of cerebral collateral circulation on prognosis of the patients with intravenous thrombolysis HUANG Guang-jian, GAO Wen, QIN Hui-xun,et al. Department of Neurology,The People’s Hospital of Liuzhou,Liuzhou, Guangxi Zhuang Autonomous Region 545006,China |
|
Huang Guang-jian, Qin Hui-xun, Chen Hong, Yang Ming-xiu, Zhang Jie-de, Fu Lin, Tang Yi-si, Qin Bin, Qin Cheng
|
|
The People’s Hospital of Liuzhou
|
| Abstract: |
| Objective To use the DSA to evaluate the cerebral collateral circulation and analyze its effect on prognosis of the patients with acute ischemic stroke treated with intravenous thrombolysis. Methods The clinical data of 121 patients enrolled in the stroke center of our hospital from January 2018 to December 2019 who received intravenous thrombolysis therapy and DSA examination were collected and analyzed. According to the DSA results, the patients were divided into two groups: the good collateral circulation compensation (53 cases,grade 3-4) and the poor collateral circulation compensation (68 cases,grade 0-2). Results The volume of cerebral infarction in the group with good collateral circulation compensation was significantly smaller than that in the poor group (p＜0.05), and the complications of hemorrhage after thrombolysis were also lower in the good group (p＜0.05). Compared with those before thrombolysis, the NIHSS scores in the two groups were significantly reduced assessed after thrombolysis at7 days、3 months and 6 months (all p＜0.05). Also,the ADL scores of patients in both groups were significantly increased at 7 days, 3 months and 6 months after thrombolysis (all p < 0.05). Compared with the group with poor collateral circulation compensation, the NIHSS scores of the good group assessed before thrombolysis and after thrombolysis at 7 days、3 months and 6 months were significantly lower than the poor group (all p < 0.05).Meanwhile, the ADL scores of the good group assessed before thrombolysis and after thrombolysis at 7 days、3 months and 6 months were significantly higher than the poor group (all P < 0.05). Conclusion Collateral circulation has an important influence on the efficacy and prognosis of intravenous thrombolysis in patients with acute cerebral infarction. And the good collateral circulation can significantly improve the patients’ prognosis. |
| Key words: Acute ischemic stroke Collateral circulation Intravenous thrombolysis Digital subtraction angiography |
|
|
|
|
