| 摘要: |
| ［摘要］ 目的 提高临床医生对Churg-Srauss综合征（CSS）的认识。方法 分析5例经病理学确诊CSS患者的临床特点，并复习相关文献。结果 5例CSS患者均有不同病程的哮喘表现，3例有鼻炎或鼻窦炎，心脏受累和胃肠道受累各1例。5例患者外周血嗜酸粒细胞比例>10%。胸部影像学检查5例均表现肺部实变影，3例肺部实变影多变。所有病例经糖皮质激素或联合免疫抑制剂治疗后均缓解。结论 哮喘、外周血嗜酸粒细胞增多和肺部实变影多变是CSS的临床特点，糖皮质激素和免疫抑制剂是主要治疗药物。 |
| 关键词: 血管炎 Churg-Srauss综合征 嗜酸粒细胞 |
| DOI：10.3969/j.issn.1674-3806.2009.08.11 |
| 分类号:R 562.2 |
| 基金项目: |
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| A report of 5 cases of Churg-Srauss syndrome |
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QIN Zhi-qiang, WEI Hai-ming, LU Ai-ling, et al.
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Department of Respiratory Disease, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective The diagnosis of Churg-Srauss syndrome (CSS) keeps difficult during clinical practice. To enhance the knowledge of CSS, 5 cases of this disorder were reported.Methods The clinical data of 5 patients with CSS were analyzed and related literatures were reviewed.Results At the time of diagnosis, all of the 5 patients with CSS presented with asthma, rhinitis or paranasal sinusitis was found in 3 patients, heart and gastrointestinal tract were involved in 1 patient, respectively. Five patients had eosinophilia of >10% white blood cell. The major radiographic findings showed pulmonary infiltrates in 5 patients, which were transient patterns in 3 patients. All patients achieved remission by corticosteroid or combination with immunosuppressant.Conclusion Asthma, peripheral blood eosinophilia and migratory pulmonary consolidation are the clinical features of CSS. Corticosteroid or immunosuppressant adjunction to corticosteroid benefits this disease. |
| Key words: Vasculitis Churg-Srauss syndrome Eosinophilia |
