| 摘要: |
| ［摘要］ 目的 探讨原发性高血压患者脂代谢与颈动脉粥样硬化的关系。方法 检测122例原发性高血压患者（观察组）与34例血压正常者（对照组）的血总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、载脂蛋白A、载脂蛋白B、脂蛋白a水平，同时进行颈动脉超声检查。结果 与对照组比较，观察组颈动脉内-中膜明显增厚、斑块形成明显增多；甘油三酯、低密度脂蛋白胆固醇、载脂蛋白B、脂蛋白a明显增高。结论 原发性高血压患者的脂类代谢异常与颈动脉内-中膜增厚及斑块形成有关。及时检测原发性高血压患者的血脂和颈动脉粥样硬化情况，评价病变程度，对疾病的早期防治具有重要的价值。 |
| 关键词: 高血压 动脉粥样硬化 脂代谢 |
| DOI：10.3969/j.issn.1674-3806.2009.11.09 |
| 分类号:R 544.1 |
| 基金项目: |
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| Relationship between lipid metabolism and carotid atherosclerosis in essential hypertensive patients |
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WANG Rong-gui, LIANG Hao
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Department of Neurology, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To investigate the relationship between lipid metabolism and carotid atherosclerosis in essential hypertensive patients.Methods The total cholesterol(TC), triglyceride(TG)，HDL-C, LDL-C, ApoA, ApoB, lipoprotein-a were tested and carotid artery ultrasonography were undergone in 122 essential hypertensive patients (observed group) and 34 normotensive persons (control group).Results Compared with control group, the intima-media thickness was thicker, the number of atherosclerotic plaques was larger and the level of TG，LDL-C, ApoB, lipoprotein-a were higher in observed group.Conclusion Abnormal lipid metabolism is related to the intima-media thickness and formation of plaque in hypertensive patients. Timely detecting the level of blood lipid and degree of carotid atherosclerosis, and evaluating the degree of patholoic change has important effect in early preventing and treating for hypertensive patients. |
| Key words: Hypertension Carotid atherosclerosis Lipid metabolism |
