| 摘要: |
| ［摘要］ 目的 探讨玉林市妇女宫颈人类乳头状瘤病毒（HPV）感染状况，为预防HPV感染和宫颈癌防治提供理论依据。方法 采用香港凯普生物科技有限公司生产的专用采样刷取宫颈脱落细胞对玉林市862例妇女进行HPV检测，并对HPV-DNA亚型情况进行分析。结果 862份宫颈标本中共检出HPV感染165例，阳性率为19.14%。其中19～30岁组HPV感染率为19.44%；31～45岁组HPV感染率为18.60%；46～70岁组HPV感染率为20.45%，各年龄组的HPV感染差异无统计学意义（P>0.05）。HPV的分型状况：18种为亚型（214例次），高危亚型占73.36%。高危亚型检出12个亚型（包括HPV16、18、31、33、35、39、45、51、52、58、59、68）157例次，HPV高危亚型首位是HPV16占高危亚型的27.39%，依次为HPV52占26.11%，HPV58占14.01%，HPV18占10.83%，HPV31占3.18%。低危型HPV检出6种亚型（包括HPV11、43、53、6、66、CP8304）57例次，占26.63%。结论 高危型HPV感染是诱发宫颈癌的病因学因素，筛查、控制HPV感染能有效降低宫颈癌的发病率。 |
| 关键词: 宫颈 人类乳头状瘤病毒 HPV分型 感染 |
| DOI：10.3969/j.issn.1674-3806.2009.12.16 |
| 分类号:R 737.33 |
| 基金项目: |
|
| Infection condition of cervix humanpapillomavirus infection in 862 women in Yulin |
|
LUO Yu-di, DENG Guo-sheng
|
|
Women and Children Health Hospital Of Yulin City, Guangxi 537000, China
|
| Abstract: |
| ［Abstract］ Objective To discuss the infection condition of cervix humanpapillomavirus(HPV) in women in the Yulin, provide the theory basis for preventing the HPV infection and preventing and treating cervical cancer.Methods The special-purpose sampling brush for cervix cast-off cells which was produced by the Hong Kong Kaipu biotechnology Co.LTD was used to take the uterus cast-off cells to carry on the HPV examination in the Yulin′s 862 women, and the HPV-DNA subtypes were analyzed.Results There were 165 women with HPV infection in 862 women cervix samples, the positive rate was 19.14%. And the HPV infection′s percentage of the 19～30 -years -old group was 19.44%;the 31～45 -years- old group′s was 18.60%;the 46～70- years-old group′s was 20.45%, the HPV infection′s differences were not evident among the various age groups. The HPV′s distributing condition showed, there were 18 kinds of subtypes, 214 case-times, the high-risk subtype accounted for 73.36%.There were 12 high-risk subtypes (including HPV16, 18, 31, 33, 35, 39, 45, 51、52, 58, 59、68), 157 case-times, the first place of HPV high-risk subtype was HPV16, which accounted for 27.39%, other subtypes were as followings: HPV52 accounted for 26.11%;HPV58, accounted for 14.01%;HPV18, accounted for 10.83%; HPV31, accounted for 3.18%. There were 6 low-risk subtypes (including HPV11, 43, 53, 6, 66, CP8304), 57 case-times, accounted for 26.63%. Conclusion The high-risk HPV infection is the etiology factor inducing cervical cancer, and screening, controlling the HPV infection can reduce the cervical cancer′s incidence rate effectively. |
| Key words: Cervix Humanpapillomavirus HPV subtype Infection |
