| 摘要: |
| ［摘要］ 目的 了解本地区泌尿生殖道支原体感染及耐药状况，为临床治疗提供依据。方法 对本院送检的8 041份泌尿生殖道分泌物标本进行支原体培养及药敏试验。结果 8 041份标本中共培养出支原体阳性标本3 607份，阳性率44.86%。其中解脲支原体(Uu)3 034株,占84.11%，人支原体(Mh)27株,占0.75%，Uu+Mh混合为546株,占15.14%；支原体对12种抗菌药物的耐药率从高到低依次为环丙沙星80.68%(2910/3607)、加替沙星58.28%(2102/3607)、可乐必妥52.50%(1894/3607)、红霉素42.20%(1522/3607)、罗红霉素33.40%(1205/3607)、甲砜霉素30.88%(1114/3607)、克拉霉素25.20%(909/3607)、阿歧霉素24.84%(896/3607)、环脂红霉素22.46%(810/3607)、强力霉素13.47%(486/3607)、美满霉素12.89%(465/3607)、交沙霉素3.08%(111/3607)。结论 Uu是泌尿生殖道最常见的病原体，多发年龄段为21～30岁，与不孕不育有关。耐药率最低的药物是交沙霉素，美满霉素和强力霉素次之。 |
| 关键词: 泌尿生殖道 支原体 药敏试验 耐药率 |
| DOI：10.3969/j.issn.1674-3806.2010.02.15 |
| 分类号:R 518.9 |
| 基金项目: |
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| Analysis of drug resistance of Mycoplasma infection in urogenital tract |
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QIU Xiao-xia
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Maternal and Child Care Hospital of Guangxi Province,Nanning 530003,China
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| Abstract: |
| ［Abstract］ Objective To evaluate the status of drug resistance in Mycoplasma infection in urogenital tract,and provide evidences for clinical therapy. Methods Mycoplasma from urogenital tract secretion samples （n=8 041） of our hospital were artificially cultivated and taken drug sensitive tests. Results Positive rates of Mycoplasma was 44.86% （3 670 in 8 041）, among which ureaplasma urealyticum accounted for 84.11% (3 034 in 3 607), Mycoplasma hominis accounted for 0.75%(27 in 3 607), Mixed infextion accounted for 15.14%(546 in 3 607); resistances of Mycoplasma to 12 antibacterials reduced successively: ciprofloxacin 80.68%(2910/3607), gatifloxacin 58.28%(2102/3607), cravit 52.50%(1894/3607), erythromycin 42.20%(1522/3607), roxithromycin 33.40%(1205/3607), thiamphenicol 30.88%(1114/3607), clarithromycin 25.20%(909/3607), azithromycin 24.84%(896/3607), alicyclic- erythromycin 22.46% (810/3607), doxycycline 13.47%(486/3607)， minocycline 12.89%(465/3607)， josamycin 3.08%(111/3607). Conclusion Ureaplasma urealyticum (Uu) is the most familiar pathogen in urogenital tract, which usually occurs between the ages 21and 30 years, relates to infertility. Resistance to Josamycin was the lowest, Minocycline and Doxycycline take second place. |
| Key words: Urogenital tract Mycoplasma Drug sensitivity test Drug resistance |
