| 摘要: |
| ［摘要］ 目的 观察喷他佐辛对腹腔镜胆切除术(LC)是否具有超前镇痛作用。方法 将60例择期LC患者(ASA分级Ⅰ～Ⅱ级)随机分为研究组和对照组。观察24 h内恶心、呕吐、瘙痒等不良应的发生率。研究组在全麻诱导前静脉缓慢推注喷他佐辛0.5 mg/kg。对照组给予生理盐水推注。记录自主呼吸恢复时间、睁眼时间、拔管时间及术后1、2、4、8、12、24 h的疼痛程度并进行评价。结果 两组呼吸恢复时间、睁眼时间、拔管时间差异无统计学意义（P>0.05）；研究组疼痛程度明显低于对照组(P<0.05)；术后患者的并发症的发生情况差异无统计学意义(P>0.05)。结论 术前应用喷他佐辛0.5 mg/kg能有效减轻腹腔镜胆囊切除术的术后疼痛，起到超前镇痛作用，是一种理想的长效中枢性镇痛方法。 |
| 关键词: 喷他佐辛 腹腔镜胆囊切除术 超前镇痛 |
| DOI：10.3969/j.issn.1674-3806.2010.03.16 |
| 分类号:R 614.3 |
| 基金项目: |
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| The application of pentazocine preemptive analgesia in laparoscopic cholecystectomy |
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SUN Nai,LIU Xiao-gang,LI Zheng-kai
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Department of Anesthesiology,the Central Hospital of Zhengzhou City,Henan 450007,China
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| Abstract: |
| ［Abstract］ Objective To observe the role of preemptive analgesia of pentazocine in laparoscopic cholecystectomy (LC).Methods Sixty patients with elective LC (ASA grade Ⅰ to grade Ⅱ) were randomly divided into pre-emptive analgesia group and the control group. Within 24 h, the incidence of nausea, vomiting, itching, etc. were observed. Pre-emptive analgesia group (A group) received intravenous slow bolus injection of pentazocine 0.5 mg/kg, induction of general anesthesia. The control group (B group) were injected with saline. The spontaneous breathing recovery time, eyes open time and extubation time and pain assessment at 1, 2, 4, 8, 12, 24 h of treatment were recorded.Results The difference in breathing recovery time, eyes open time and extubation time between two groups was not statistically significant (P>0.05). The pain intensity in A group was significantly lower than that in group (P<0.05). The occurrence of postoperative complications between two groups was no significant difference (P>0.05). Conclusion Preoperative application of pentazocine 0.5 mg/kg can effectively reduce the postoperative laparoscopic cholecystectomy pain, with a role of preemptive analgesia,is an ideal long-term central analgesia. |
| Key words: Pentazocine Laparoscopic cholecystectomy Preemptive analgesia |
