| 摘要: |
| ［摘要］ 目的 探讨早发型子痫前期的临床特点及围产儿结局。方法 回顾性分析2004-01～2009-12间524例子痫前期病例的有关临床资料，根据孕周将其分为早发组（<32周）,晚发组（≥32周），比较两组病例发病情况、病情特点及母婴并发症等。结果 与晚发组子痫前期相比，早发型子痫前期具有明显的高血压家族史(P<0.01)；易发展成重度子痫前期(P<0.01)，出现肝、肾功能损害(P<0.01)；围产儿病死率高(P<0.01)。分娩孕期与围产儿预后显著相关(P<0.05)。结论 早发型子痫前期对孕妇的危害主要是围产儿不良结局发生率增高。 |
| 关键词: 早发型子痫前期 临床特征 预后 |
| DOI：10.3969/j.issn.1674-3806.2010.08.10 |
| 分类号:R 714.24 |
| 基金项目: |
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| Clinical features and prognostic analysis of early-onset preeclampsia |
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HUANG Ling-ling, ZHONG Lin-lin, SU Sha
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Department of Obstetrics, the First Affliated Hospital of Guangxi Medical University,Nanning 530021, China
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| Abstract: |
| ［Abstract］ Objective To evaluate the clinical features and perinatal outcome of early-onset preeclampsia (PE). Methods A retrospective analysis of 524 cases of preeclampsia from January 2004 to December 2009 was performed. All the patients were divided into two groups according to gestational week: early-onset preeclampsia group (<32 weeks) and lately-onset preeclampsia group (≥32 weeks). The data were analyzed on the incidence，manifestation， maternal and fetal complications. Results Compared with the lately-onset preeclampsia group, the early-onset preeclampsia group had significant family history of hypertension and preeclampsia (P<0.01); easily developed into severe preeclampsia and renal dysfunction and hepatic dysfunction (P<0.01); had high perinatal mortality (P<0.01); The gestational time at delivery was significantly correlated with perinatal prognosis (P<0.05). Conclusion Early-onset preeclampsia is a severe type of preeclampsia, which has high perinatal mortality. |
| Key words: Early-onset preeclampsia Clinical features Prognosis |
