引用本文:邓 燕,秦 雪,黄 珊,廖湘成,伍惠玲,张海英,李 山.广西防城港地区汉族健康成年男性血清叶酸和维生素B12正常参考值的建立[J].中国临床新医学,2011,4(5):413-416.
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广西防城港地区汉族健康成年男性血清叶酸和维生素B12正常参考值的建立
邓 燕,秦 雪,黄 珊,廖湘成,伍惠玲,张海英,李 山
530021 南宁,广西医科大学第一临床学院(邓 燕,黄 珊,廖湘成,伍惠玲),广西医科大学第一附属医院临床医学实验部(秦 雪,李 山),广西医科大学科研部(张海英)
摘要:
[摘要] 目的 建立广西防城港地区汉族健康成年男性血清叶酸和维生素B12的正常参考值范围。方法 通过电化学发光法测定2 021例20~69岁的健康成年男性血清叶酸和维生素B12水平。结果 广西防城港地区汉族健康成年男性的血清叶酸各年龄段正常参考值范围分别为20~29岁8.56(4.97~14.71)ng/ml,30~39岁9.25(5.24~15.42)ng/ml,40~49岁9.66(5.35~16.38)ng/ml,50~59岁9.31(5.49~16.60)ng/ml,60~69岁9.44(4.58~14.86)ng/ml。广西防城港地区汉族健康成年男性的血清维生素B12各年龄段正常参考值范围分别为20~29岁639.80(295.68~1 196.75)pg/ml,30~39岁665.10(325.70~1 201.00)pg/ml,40~49岁690.70(250.55~1 214.50)pg/ml,50~59岁710.30(331.34~1 343.70)pg/ml,60~69岁699.85(180.42~1 446.88)pg/ml。结论 各地区各实验室应建立各自的健康人群的正常参考值范围,尤其是那些具有特殊饮食和生活习惯的地区。
关键词:  叶酸  B12  正常参考值
DOI:10.3969/j.issn.1674-3806.2011.05.08
分类号:Q 592.1
基金项目:广西自然科学基金资助项目(编号:2010GXNSFA013174);广西2010年研究生教育创新计划资助项目(编号:2010105981002M198)
Reference values for serum levels of B12 and folate in Han ethnic males from the Fangchenggang area
DENG Yan, QIN Xue, HUANG Shan, et al.
Guangxi Medical University, Nanning 530021, China
Abstract:
[Abstract] Objective To establish the normal reference values of serum folic acid and vitamin B12 among the male Han people of the Fangchenggang area of Guangxi.Methods Roche Cobas E601 electrochemical immunoassay was used to measure the serum folate and vitamin B12 levels among the 2 021 male Han people aged 20~69.Results Normal reference values of serum folic acid among the male Han people of the Fangchenggang area of Guangxi were: 8.56(4.97~14.71)ng/ml in 20~29 years, 9.25(5.24~15.42)ng/ml in 30~39 years, 9.66(5.35~16.38)ng/ml in 40~49 years, 9.31(5.49~16.60)ng/ml in 50~59 years, 9.44(4.58~14.86)ng/ml in 60~69 years. Normal reference values of vitamin B12 among the male Han people of the Fangchenggang area of Guangxi were: 639.80(295.68~1 196.75)pg/ml in 20~29 years, 665.10(325.70~1 201.00)pg/ml in 30~39 years, 690.70(250.55~1 214.50)pg/ml in 40~49 years, 710.30(331.34~1 343.70)pg/ml in 50~59 years, 699.85(180.42~1 446.88)pg/ml in 60~69 years.Conclusion It is suggested that every region should establish respective normal reference values of healthy person, especially the region which have different diet and lifestyle habits.
Key words:  Folate  Vitamin B12  Reference values