| 摘要: |
| ［摘要］ 目的 探讨抗甲状腺药物治疗两种彩超不同声像特征原发性甲亢的疗效。方法 随机选择均匀回声型（均匀组）及不均匀回声型（不均匀组）原发性甲亢患者各31例，两组均用抗甲状腺药物治疗，于治疗前后检测甲状腺功能、甲状腺抗体，同时对甲状腺进行彩超检查，观察甲状腺声像、彩色血流分布，检测甲状腺大小及上动脉血流频谱参数。结果 两组治疗前各检测指标差异无统计学意义（P>0.05），经抗甲状腺药物治疗后两组疗效比较差异有统计学意义（P<0.01）。均匀回声型治疗效果明显优于不均匀回声型（P<0.01），不均匀回声型组其危险度高于均匀回声型组（OR=12.923,P＝0.000，95%CI:3.225～51.781）。结论 抗甲状腺药物对原发性甲亢均匀回声型疗效较好，对不均匀回声型疗效较差，这对临床治疗方法的选择有重要的参考意义。 |
| 关键词: 原发性甲亢 抗甲状腺药物 疗效 |
| DOI：10.3969/j.issn.1674-3806.2011.09.02 |
| 分类号:R 581.1 |
| 基金项目:广西科技厅青年基金资助项目（编号：桂科青0339019） |
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| Observation of curative effects of antithyroid drug on the patients with primary hyperthyroidism of different imaging |
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XU Chun-mei, ZHU Shang-yong, LIU Hong-yan,et al.
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Department of Ultrasonography, the People′s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021,China
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| Abstract: |
| ［Abstract］ Objective To investigate the curative effects of antithyroid drug (ATD) on the patients with primary hyperthyroidism (PHT) of different imaging. Methods Sixty-two patients with PHT of different imaging ［homogeneous echo (n=31) and inhomogeneous echo (n=31) ］ were randomly chosen and were treated with ATD. The volume of thyroid gland (V) was examined by using B-ultrasound and systolic and diastolic blood flow velocity (Vmax, Vmin) and resistance index (RI) were examined by using CDFI in these two groups. Serum levels of TT3, TT4, FT3, FT4, TSH, TRH, TRAb, TGAb and TMAb were also assayed before and after treatment. Results There was no significant difference in V, Vmax, Vmin, RI, or FT3, FT4, TSH, TRAb before treatment（P>0.05）, but significant difference after treatment in the curative effects between the two groups (P<0.05）. The curative effects in homogeneous echo group was better than that in inhomogeneous echo group (P<0.05）. Conclusion ATD treatment has good curative effects on the patients with PHT of homogeneous echo,but bad curative effects on those of inhomogeneous echo. It is very important in treatment. |
| Key words: Primary hyperthyroidism Antithyroid drug Curative effects |
