| 摘要: |
| ［摘要］ 目的 探讨在超重及肥胖患者中，血清白细胞介素-6(IL-6)、C-反应蛋白(CRP)水平变化及意义。方法 选择37例正常体重者和42例超重及肥胖患者,常规测量血压、体重、身高,计算体重指数，抽取空腹静脉血检测其血糖、血脂、胰岛素、IL-6、CRP。结果 与正常体重人群相比，在超重及肥胖患者中,收缩压、甘油三酯、IL-6及CRP水平均高于正常体重组（P<0.05）。在超重及肥胖患者中,血清IL-6、CRP水平均与肥胖相关指数呈正相关。结论 在超重及肥胖人群中,血清IL-6、CRP水平增高与体重指数呈正相关，超重及肥胖与炎症密切相关。 |
| 关键词: 超重及肥胖 白细胞介素-6 C-反应蛋白 |
| DOI：10.3969/j.issn.1674-3806.2011.10.10 |
| 分类号:R 589.2 |
| 基金项目: |
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| Research on the serum leves of IL-6 and CRP in overweight and obesity persons |
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WANG Quan-ming,PENG Yun-bo,QIN Yong-qi
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Department of First Internal Medicine,Nandan County People′s Hospital,Guangxi 547200,China
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| Abstract: |
| ［Abstract］ Objective To explore the serum levels of IL-6 and CRP in overweight and obesity persons.Methods Thirty-seven normal weight persons and 42 overweight and obesity persons were taken fasting blood samples for measurements of plasma glucose, plasma lipids, insulin, C-reactive protein(CRP),interleukin-6 (IL-6).Results The levels of IL-6 in overweight and obesity persons were significant higher than those in the normal weight persons（P<0.05）. Pearson relation analysis showed that serum IL-6 and CRP levels were positively and significantly correlated with body mass index.Conclusion The levels of serum IL-6 and CRP were higher in overweight and obesity persons, and suggests that inflammation might be closely correlated to overweight and obesity. |
| Key words: Overweight and obesity IL-6 CRP |
