摘要: |
[摘要] 目的 探讨戒烟药物伐尼克兰的服用时间长短与戒烟效果的关系。方法 观察自愿戒烟的吸烟者25例,均采用伐尼克兰治疗,服药后第2、第4、第6、第8、第12 W进行电话随访,对吸烟者的服药时间及戒烟情况进行记录和分析。结果 在25例吸烟者中,9~12 W戒烟成功者12例,占48%(12/25),戒烟未成功者13例,占52%(13/25)。戒烟成功者的服药时间平均为7.23 W,明显长于戒烟未成功者的4.83 W(P=0.011),服药时间较长者(8~12 W)戒烟成功率高于服药时间较短者(<8 W)(P=0.027)。结论 伐尼克兰戒烟有确切的效果,戒烟效果与服药时间长短有关。 |
关键词: 吸烟 伐尼克兰 戒烟 |
DOI:10.3969/j.issn.1674-3806.2011.12.20 |
分类号:R 163.2 |
基金项目: |
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Clinical observation of varenicline for smoking cessation |
LIANG Da-hua, LIU Hang, WEI Cai-zhou
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Department of Respiratory Disease, the People′s Hospital of Guangxi Zhuang Autonomous Region,Nanning 530021,China
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Abstract: |
[Abstract] Objective To observed the relationship between times and effects of treatment with varenicline for smoking cessation.Methods Twenty-five smokers who wish smoking cessation were observed. They were treated by varenicline, and the telephone follow-up were performed at weeks 2, 4, 6, 8 and 12 after treatment,and the times of treatments and abstinence were recorded and analysis.Results The numbers of continuous abstinence participants were 12 from 9 to 12 weeks, and continuous abstinence rates were 48% (12/25). The number of discontinuing abstinence participants were 13, and discontinuation rates were 52% (13/25). The average duration of treatment with varenicline was 7.23 weeks in continuous abstinence participants, and it was longer than that in discontinuing abstinence participants (P=0.011). The continuous abstinence rates in longer-times of treatment (8~12 weeks) was higher than that in shorter-times of treatment (P=0.027).Conclusion Varenicline was an efficacious pharmacotherapy for smoking cessation. The effect of treatment was related to times of treatment with varenicline. |
Key words: Smoking Varenicline Smoking cessation |