| 摘要: |
| ［摘要］ 目的 观察不同用药方法阻断艾滋病母婴传播效果。方法 2005～2007年应用维乐命方案（方案1）阻断HIV母婴传播26例，2008～2010年联合应用三联抗病毒药物方案（方案2）阻断HIV母婴传播47例。所出生的婴儿均采用人工喂养，随访观察至18月龄。结果 两种方案出生的婴儿外观均未见畸形，方案1出现2例婴儿HIV阳性（母儿均服药及仅婴儿服药各1例）；方案2出现1例婴儿HIV阳性（仅婴儿服药），母儿均服药均为阴性。结论 对HIV阳性孕妇采取综合干预措施(抗病毒药物治疗、婴儿人工喂养)能有效阻断HIV母婴传播。 |
| 关键词: 艾滋病病毒感染 孕妇 母婴传播 |
| DOI：10.3969/j.issn.1674-3806.2012.07.20 |
| 分类号:R 512.91 |
| 基金项目: |
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| Clinical observation of different medication in the block of mother-to-infant transmission of HIV in 73 pregnant women |
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HUANG Nuan-ying, LIANG Yan-fen
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Department of Obstetrics and Gynaecology, Luzhai Maternal and Child Health Hospital, Guangxi 545600, China
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| Abstract: |
| ［Abstract］ Objective To research the prevention effect of different medication on mother-to-infant transmission of HIV.Methods Seventy-three HIV-positive pregnant women were chosen. Of them, 26 women were treated by the Nevirapine tablet from 2005 to 2007 (scheme 1)，and 47 women were treated by the combined application of triple antiviral drug from 2008 to 2010 (scheme 2). Their infants were follow up for 18 months. All the infants were used artificial feeding.Results There was no deformity infant within the two schemes. There were 2 HIV-positive infants in scheme 1.(One infant was from the group that the mathers and the infants were both treated, and the other infant was from the group that only the infants were treated). There was only 1 HIV-positive infant in scheme 2.(The infant was from the group that only the infants were treated). All the other infants were negative in scheme 2 in which the mathers and the infants were both treated.Conclusion To take comprehensive intervention measures in the HIV-positive pregnant women is an effective way to block the mother-to-infant transmission of HIV. The measures include treating by antiviral drug and artificial feeding. |
| Key words: AIDS virus infection Pregnant woman Mother-to-infant transmission |
