引用本文:阳世雄,王斌强,曾建业,韦涌初,黄思光.孤立性肺结节恶性病变的危险因素分析[J].中国临床新医学,2012,5(8):707-710.
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孤立性肺结节恶性病变的危险因素分析
阳世雄,王斌强,曾建业,韦涌初,黄思光
530031 广西,南宁市第二人民医院心胸外科
摘要:
[摘要] 目的 探讨孤立性肺结节恶性病变的危险因素。方法 统计120例孤立性肺结节的临床特征,对这些临床特征与孤立性肺结节的性质之间的关系作单因素分析,进一步对有统计学意义者作多因素分析。结果 120例中有64例(53.3%)术后病检结果为恶性病变。单因素分析中,吸烟史、结节大小、年龄及影像学表现4个因素差异具有统计学意义。多因素分析中年龄、影像学表现两个因素差异具有统计学意义。结论 吸烟史、结节大小、年龄及影像学表现,尤其是后二者是孤立性肺结节恶性病变的危险因素,综合分析这些因素,可提高对孤立性肺结节良恶性判断的准确性。
关键词:  孤立性肺结节  危险因素  诊断
DOI:10.3969/j.issn.1674-3806.2012.08.05
分类号:R 563
基金项目:广西科技开发项目(编号:桂科攻0816004-18)
Analysis on risk factors of malignant solitary pulmonary nodule
YANG Shi-xiong, WANG Bin-qiang,ZENG Jian-ye,et al.
Department of Cardiology and Thoracic Surgery, the Second People′s Hospital of Nanning, Guangxi 530031, China
Abstract:
[Abstract] Objective To investigate the risk factor of malignant solitary pulmonary nodule(SPN).Methods A monovariate analysis was used for exploring the correlation between clinical characteristics and pathological characteristics in 120 patients with SPN and then a multivariate analysis was performed in the factors with significant difference.Results Sixty-four patients postoperatively were proved to be malignant SPN.There was significant correlation between four factors(namely smoking,nodule size,age,image characteristics) and pathological characteristics in monovariate analysis.However only two factors(age and image characteristics)were left in multivariate analysis.Conclusion Smoking,nodule size,age and image characteristics,especially age and image characteristics,are the risk factors of malignant SPN. With a overall analysis for these factors,doctors can improve diagnosis accuracy of SPN.
Key words:  Solitary pulmonary nodule(SPN)  Risk factor  Diagnosis