摘要: |
[摘要] Th22细胞亚群是新发现的一类T细胞亚群,分泌白细胞介素-22、白细胞介素-13、白介素-6等细胞因子,而不产生干扰素-γ、白细胞介素-4和白细胞介素-17。其功能主要通过白细胞介素-22来实现,介导炎症反应、自身免疫性疾病、肿瘤等的发生发展,在机体免疫调节、宿主防御及组织修复中发挥重要作用。该文对Th22细胞的研究进展作一简要综述。 |
关键词: Th22细胞 白细胞介素-22 自身免疫性疾病 |
DOI:10.3969/j.issn.1674-3806.2013.05.34 |
分类号:R 543.1+2 |
基金项目: |
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The new research progress of Th22 cells |
LU Shan-he, LIN Ying-zhong
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Department of Cardiology, the People’s Hospital of Guangxi Autonomous Region,Nanning 530021,China
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Abstract: |
[Abstract] T helper cell 22(Th22) is a new subset of T cells.They mainly secrete interleukin(IL)-22,IL-13 and IL-6,but not interferon-γ(IFN-γ) or IL-4 or IL-17,and exert their function mainly via IL-22.They can mediate inflammatory reactions,autoimmune diseases,tumors,etc,and play an important role in immune regulation,host defense and tissue repair.This paper reviewed the research progress of Th22. |
Key words: Th22 cells Interleukin-22 Autoimmune diseases |